Prenatal sevoflurane exposure: Effects of iron metabolic dysfunction on offspring cognition and potential mechanism

Y Zuo, Y Chang, A Thirupathi… - International Journal of …, 2021 - Wiley Online Library
For decades, the neurotoxicity caused by anesthetics in mammalian brain development has
gained increasing attention. Exposure to anesthetics leads to neurotoxicity and apoptosis of …

Role of anesthetics and their adjuvants in neurovascular protection in secondary brain injury after aneurysmal subarachnoid hemorrhage

U Athiraman, GJ Zipfel - International journal of molecular sciences, 2021 - mdpi.com
Aneurysmal rupture accounts for the majority of subarachnoid hemorrhage and is
responsible for most cerebrovascular deaths with high mortality and morbidity. Initial …

Sevoflurane protects against intracerebral hemorrhage via microRNA-133b/FOXO4/BCL2 axis

L Li, Y Zhan, H Xia, Y Wu, X Wu, S Chen - International …, 2023 - Elsevier
Abstract The application of Sevoflurane (Sev) in neurological diseases has been
documented. We herein clarified the role of Sev in intracerebral hemorrhage (ICH). Through …

Sevoflurane and desflurane exposures following aneurysmal subarachnoid hemorrhage confer multifaceted protection against delayed cerebral ischemia

K Jayaraman, M Liu, GJ Zipfel, U Athiraman - Biomedicines, 2021 - mdpi.com
Numerous studies have demonstrated the ability of isoflurane conditioning to provide
multifaceted protection against aneurysmal subarachnoid hemorrhage (SAH)-associated …

Inhalational Versus Intravenous Anesthetic Conditioning for Subarachnoid Hemorrhage–Induced Delayed Cerebral Ischemia

U Athiraman, AV Lele, M Karanikolas, VB Dhulipala… - Stroke, 2022 - Am Heart Assoc
Background: Inhalational anesthetics were associated with reduced incidence of
angiographic vasospasm and delayed cerebral ischemia (DCI) in patients with aneurysmal …

Conditioning-based therapeutics for aneurysmal subarachnoid hemorrhage–A critical review

S Pugazenthi, AJ Norris, DC Lauzier… - Journal of Cerebral …, 2024 - journals.sagepub.com
Aneurysmal subarachnoid hemorrhage (SAH) carries significant mortality and morbidity,
with nearly half of SAH survivors having major cognitive dysfunction that impairs their …

[HTML][HTML] The protective effects of sevoflurane on subarachnoid hemorrhage

W Xing, J Zhao, J Liu, Z Liu, G Chen - Medical Gas Research, 2024 - journals.lww.com
Sevoflurane has become an important volatile anesthetic in clinic and has been widely
studied in recent years. Numerous studies have demonstrated the efficacy of sevoflurane in …

Sevoflurane dampens acute pulmonary inflammation via the adenosine receptor A2B and heme oxygenase-1

KC Ngamsri, A Fuhr, K Schindler, M Simelitidis… - Cells, 2022 - mdpi.com
Acute respiratory distress syndrome is a life-threatening disease associated with high
mortality. The adenosine receptor A2B (Adora2b) provides anti-inflammatory effects, which …

[Retracted] Meta‐Analysis of Anesthetic Efficacy and Safety of Propofol in Craniotomy Patients

Q Zhou, Y Han, J Chen - Contrast Media & Molecular Imaging, 2022 - Wiley Online Library
The anesthetic effect and safety of propofol in craniotomy patients by meta‐analysis is
investigated. Relevant studies consistent with the anesthetic effect and safety of propofol in …

Volatile Sedation in Neurointensive Care Patients After Aneurysmal Subarachnoid Hemorrhage: Effects on Delayed Cerebral Ischemia, Cerebral Vasospasm, and …

J Küchler, B Schwachenwald, MV Matone… - World Neurosurgery, 2024 - Elsevier
Background Volatile anesthetics have shown neuroprotective effects in preclinical studies,
but clinical data on their use after aneurysmal subarachnoid hemorrhage (aSAH) are limited …