The extracellular matrix (ECM) is a network of different proteins and proteoglycans that
controls differentiation, migration, repair, survival, and development, and it seems that its …

Adipose tissue is one of the main sources of inflammatory mediators, with interleukin-6 (IL-6)
among them. Although high systemic levels of inflammatory mediators are cachectogenic …

Intermittent fasting (IF) and energy-restricted diets (ERDs) have emerged as dietary
approaches to decrease inflammatory status; however, there are no consistent results …

Background Investigations performed in mice and humans have acknowledged obesity as a
low-grade inflammatory disease. Several molecular mechanisms have been convincingly …

The tissue composition of polyunsaturated fatty acids is important to health and depends on
both dietary intake and metabolism controlled by genetic polymorphisms that should be …

Oral Diseases (2011) 18, 16–31 A reduction in calorie intake [caloric restriction (CR)]
appears to consistently decrease the biological rate of aging in a variety of organisms as …

All diseases have a genetic predisposition. Genome-wide association studies (GWASs) by
large international consortia are discovering genetic variants that contribute to complex …

Immoderate calorie intake coupled with a sedentary lifestyle are major determinants of
health issues and inflammatory diseases in modern society. The balance between energy …

Nutrigenomics is a new application of omics technologies in nutritional science.
Nutrigenomics aims to identify molecular markers of diet-related diseases and mechanisms …

Maintaining systemic homeostasis requires the coordination of different organs and tissues
in the body. Our bodies rely on complex inter-organ communications to adapt to …