Osteogenesis imperfecta is a phenotypically and molecularly heterogeneous group of
inherited connective tissue disorders that share similar skeletal abnormalities causing bone …

Osteogenesis imperfecta is a genetic disorder characterized by low bone mass, decreased
bone strength, increased bone fragility, and shortened stature. Autosomal dominant …

Osteogenesis imperfecta (OI) is the most common inherited form of bone fragility and
includes a heterogenous group of genetic disorders which most commonly result from …

Osteogenesis imperfecta (OI) is a monogenic bone fragility disorder that usually is caused
by mutations in one of the two genes coding for collagen type I alpha chains, COL1A1 or …

On the occasion of the 13th International Conference on Osteogenesis imperfecta in August
2017 an expert panel was convened to develop an international consensus paper regarding …

Background Osteogenesis imperfecta (OI) is a rare heritable connective tissue disorder
primarily characterised by skeletal deformity and fragility, and an array of secondary …

Osteogenesis imperfecta is an inherited connective tissue disorder with wide phenotypic
and molecular heterogen-eity. A common issue associated with the molecular ab-normality …

Purpose Osteogenesis imperfecta (OI) is a genetic disorder (prevalence: 1: 10,000), leading
to bone fragility, frequent fractures, and varying degrees of physical limitations. Despite a …

Osteogenesis imperfecta (OI) is mainly characterized by bone fragility but muscle
abnormalities have been reported both in OI mouse models and in children with OI. Muscle …

Ostegenesis Imperfecta (OI) is a hereditary disease of the connective tissue caused by
mutations to, mainly, the genes that are involved in the biosynthesis of collagen type 1 …