Gastric cancer is a leading contributor to cancer incidence and mortality globally. Recently,
artificial intelligence approaches, particularly machine learning and deep learning, are …

Simple Summary Between 5% and 15% of colorectal cancers (CRC) show deficiencies in
the mismatch repair machinery and high microsatellite instability (dMMR/MSI-H). dMMR/MSI …

Novel neoadjuvant therapy regimens are warranted for oral squamous cell carcinoma
(OSCC). In this phase I trial (NCT04393506), 20 patients with locally advanced resectable …

Although antiangiogenic therapy has been used in gastric cancer, disease progression due
to drug resistance remains common. Neutrophils play an important role in the occurrence …

Immune checkpoint inhibitors have reshaped the prognostic of several tumor types,
including metastatic colorectal tumors with microsatellite instability (MSI). However, 90-95 …

Gastric cancer (GC) is one of the main causes of cancer incidence rate and mortality
worldwide. As the main breakthrough direction, the application of immune checkpoint …

Tumors have special features that make them distinct from their normal counterparts.
Immature cells in a tumor mass and their critical contributions to the tumorigenesis will open …

In the era of precision medicine, it has been increasingly recognized that individuals with a
certain disease are complex and different from each other. Due to the underestimation of the …

Background Increasing evidence indicates that leucine-rich-alpha-2-glycoprotein 1 (LRG1)
is associated with multiple malignancies, but whether it participates in gastric cancer (GC) …

Background Little is known about endogenous inhibitors of angiogenic growth factors. In this
study, we identified a novel endogenous anti-angiogenic factor expressed in pericytes and …