M1 and M2 macrophages: the chicken and the egg of immunity
The purpose of this perspective is to describe a critical advance in understanding how
immune responses work. Macrophages are required for all animal life:'Inhibit'type …
immune responses work. Macrophages are required for all animal life:'Inhibit'type …
Diversity and dialogue in immunity to helminths
JE Allen, RM Maizels - Nature Reviews Immunology, 2011 - nature.com
The vertebrate immune system has evolved in concert with a broad range of infectious
agents, including ubiquitous helminth (worm) parasites. The constant pressure of helminth …
agents, including ubiquitous helminth (worm) parasites. The constant pressure of helminth …
[HTML][HTML] Single cell RNA sequencing identifies unique inflammatory airspace macrophage subsets
Macrophages are well recognized for their dual roles in orchestrating inflammatory
responses and regulating tissue repair. In almost all acutely inflamed tissues, 2 main …
responses and regulating tissue repair. In almost all acutely inflamed tissues, 2 main …
Pulmonary macrophage subpopulations in the induction and resolution of acute lung injury
LK Johnston, CR Rims, SE Gill, JK McGuire… - American journal of …, 2012 - atsjournals.org
Macrophages are key orchestrators of the inflammatory and repair responses in the lung,
and the diversity of their function is indicated by their polarized states and distinct …
and the diversity of their function is indicated by their polarized states and distinct …
Mycobacterium tuberculosis: An Adaptable Pathogen Associated With Multiple Human Diseases
Q Chai, Y Zhang, CH Liu - Frontiers in cellular and infection …, 2018 - frontiersin.org
Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB), is an extremely
successful pathogen that adapts to survive within the host. During the latency phase of …
successful pathogen that adapts to survive within the host. During the latency phase of …
Cell origin dictates programming of resident versus recruited macrophages during acute lung injury
KJ Mould, L Barthel, MP Mohning… - American journal of …, 2017 - atsjournals.org
Two populations of alveolar macrophages (AMs) coexist in the inflamed lung: resident AMs
that arise during embryogenesis, and recruited AMs that originate postnatally from …
that arise during embryogenesis, and recruited AMs that originate postnatally from …
Mycobacterium tuberculosis-Induced Polarization of Human Macrophage Orchestrates the Formation and Development of Tuberculous Granulomas In Vitro
Z Huang, Q Luo, Y Guo, J Chen, G Xiong, Y Peng, J Ye… - PloS one, 2015 - journals.plos.org
The tuberculous granuloma is an elaborately organized structure and one of the main
histological hallmarks of tuberculosis. Macrophages, which are important immunologic …
histological hallmarks of tuberculosis. Macrophages, which are important immunologic …
Macrophage heterogeneity and plasticity in tuberculosis
Macrophages are the primary host cells for Mycobacterium tuberculosis, the causative agent
of tuberculosis (TB), during its intracellular survival in humans. The pathogen has a …
of tuberculosis (TB), during its intracellular survival in humans. The pathogen has a …
[HTML][HTML] Local arginase 1 activity is required for cutaneous wound healing
L Campbell, CR Saville, PJ Murray… - Journal of Investigative …, 2013 - Elsevier
Chronic nonhealing wounds in the elderly population are associated with a prolonged and
excessive inflammatory response, which is widely hypothesized to impede healing. Previous …
excessive inflammatory response, which is widely hypothesized to impede healing. Previous …
Protective effect of suppressing STAT3 activity in LPS-induced acute lung injury
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are diseases with
high mortality. Macrophages and neutrophils are responsible for inflammatory responses in …
high mortality. Macrophages and neutrophils are responsible for inflammatory responses in …