The Fontan operation, which places the systemic and pulmonary circulations in series and is
driven by a single ventricular chamber, is the treatment of choice for patients born with one …

The Fontan procedure has undergone many modifications since first being performed on a
patient with tricuspid valve atresia in 1968. It is now the procedure of choice for individuals …

Echocardiographic quantification is crucial in the diagnosis and management of patients
with acquired and congenital heart disease (CHD). The American Society of …

Background: The failing Fontan circulation is associated with hepatic impairment. The nature
of this liver injury is poorly defined. Objective: To establish the gross and histological liver …

Abstract Background Subjects with Fontan-type circulation have no sub-pulmonary ventricle
and thus depend exquisitely on the respiratory bellows and peripheral muscle pump for …

OBJECTIVES: The objective of this work is to evaluate the hemodynamic performance of a
new Y-graft modification of the extracardiac conduit Fontan operation. The performance of …

Background—The pulsatile nature of pulmonary blood flow is important for shear stress–
mediated release of endothelium-derived nitric oxide (NO) and lowering pulmonary vascular …

Background—Little is known about blood flow and its relationship to respiration during
exercise in patients with total cavopulmonary connection (TCPC). Methods and Results …

Purpose To implement, validate, and apply a self-gated free-running whole-heart five-
dimensional (5D) flow MRI framework to evaluate respiration-driven effects on three …

Congenital heart defects with a single functional ventricle, such as hypoplastic left heart
syndrome and tricuspid atresia, require a staged surgical approach to separate the systemic …