Acute cerebellar inflammation and related ataxia: mechanisms and pathophysiology

MSA Parvez, G Ohtsuki - Brain sciences, 2022 - mdpi.com
The cerebellum governs motor coordination and motor learning. Infection with external
microorganisms, such as viruses, bacteria, and fungi, induces the release and production of …

Drug repurposing against SARS-CoV-2 using computational approaches

S Kumar, S Kovalenko, S Bhardwaj, A Sethi… - Drug Discovery …, 2022 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
generated a critical need for treatments to reduce morbidity and mortality associated with …

[HTML][HTML] Screening and druggability analysis of some plant metabolites against SARS-CoV-2: An integrative computational approach

KF Azim, SR Ahmed, A Banik, MMR Khan… - Informatics in Medicine …, 2020 - Elsevier
The sudden outbreak of novel coronavirus has caused a global concern due to its infection
rate and mortality. Despite extensive research, there are still no specific drugs or vaccines to …

[HTML][HTML] Identification of lactoferrin-derived peptides as potential inhibitors against the main protease of SARS-CoV-2

W Zhao, X Li, Z Yu, S Wu, L Ding, J Liu - LWT, 2022 - Elsevier
COVID-19 is a global health emergency that causes serious concerns. A global effort is
underway to identify drugs for the treatment of COVID-19. One possible solution to the …

Artificial intelligence based methods for hot spot prediction

D Ovek, Z Abali, ME Zeylan, O Keskin, A Gursoy… - Current opinion in …, 2022 - Elsevier
Proteins interact through their interfaces to fulfill essential functions in the cell. They bind to
their partners in a highly specific manner and form complexes that have a profound effect on …

Fullerenes against COVID-19: Repurposing C60 and C70 to Clog the Active Site of SARS-CoV-2 Protease

TD Marforio, EJ Mattioli, F Zerbetto, M Calvaresi - Molecules, 2022 - mdpi.com
The persistency of COVID-19 in the world and the continuous rise of its variants demand
new treatments to complement vaccines. Computational chemistry can assist in the …

Identification of 4-acrylamido-N-(pyridazin-3-yl) benzamide as anti-COVID-19 compound: a DFTB, molecular docking, and molecular dynamics study

N Sepay, S Chakrabarti, M Afzal, A Alarifi, D Mal - RSC advances, 2022 - pubs.rsc.org
Omicron is one of the variants of COVID-19 and continuing member of a pandemic. There
are several types of vaccines that were developed around the globe to fight against the …

De Novo design of potential inhibitors against SARS-CoV-2 Mpro

S Li, L Wang, J Meng, Q Zhao, L Zhang, H Liu - Computers in Biology and …, 2022 - Elsevier
The impact of the ravages of COVID-19 on people's lives is obvious, and the development of
novel potential inhibitors against SARS-CoV-2 main protease (Mpro), which has been …

Identification of Promising Sulfonamide Chalcones as Inhibitors of SARS-CoV-2 3CLpro through Structure-Based Virtual Screening and Experimental Approaches

P Pojtanadithee, K Hengphasatporn… - Journal of Chemical …, 2023 - ACS Publications
3CLpro is a viable target for developing antiviral therapies against the coronavirus. With the
urgent need to find new possible inhibitors, a structure-based virtual screening approach …

[PDF][PDF] Potential of Orthosiphon aristatus Blume Miq as Antiviral: A Review: doi. org/10.26538/tjnpr/v5i3. 1

F Faramayuda, TS Mariani, E Elfahmi… - Tropical Journal of …, 2021 - researchgate.net
Orthosiphon aristatus Blume Miq is one of the commonly used medicinal plants known to
have many benefits, including antiviral activity. Components of the main secondary …