Inhibition of factor XIa as a new approach to anticoagulation

WA Schumacher, JM Luettgen, ML Quan… - … , and vascular biology, 2010 - Am Heart Assoc
The dose-limiting issue with available anticoagulant therapies is bleeding. Is there an
approach that could provide antithrombotic protection with reduced bleeding? One …

Factor XI contributes to thrombin generation in the absence of factor XII

DV Kravtsov, A Matafonov, EI Tucker… - Blood, The Journal …, 2009 - ashpublications.org
During surface-initiated blood coagulation in vitro, activated factor XII (fXIIa) converts factor
XI (fXI) to fXIa. Whereas fXI deficiency is associated with a hemorrhagic disorder, factor XII …

Screening for bovine leukocyte adhesion deficiency, deficiency of uridine monophosphate synthase, complex vertebral malformation, bovine citrullinaemia, and factor …

H Meydan, MA Yildiz, JS Agerholm - Acta Veterinaria Scandinavica, 2010 - Springer
Background Bovine leukocyte adhesion deficiency (BLAD), deficiency of uridine
monophosphate synthase (DUMPS), complex vertebral malformation (CVM), bovine …

Identification of factor XI deficiency in Holstein cattle in Turkey

H Meydan, MA Yildiz, F Özdil, Y Gedik… - Acta Veterinaria …, 2009 - Springer
Abstract Background Factor XI (FXI) is a plasma protein that participates in the formation of
blood clots. Factor XI deficiency is autosomal recessive hereditary disorder that may be …

[PDF][PDF] Deficiency in Holstein Cattle in Turkey

Y Oner, A Keskin, C Elmaci - Asian Journal of Animal and Veterinary …, 2010 - academia.edu
In this study 170 Holstein cows reared in the Bursa Region of Turkey were screened in order
to detect four autosomal recessive genetic diseases, ie, BLAD, DUMPS, citrullinamia and …

Inherited diseases of Holstein cattle: Story so far in Turkey

K Avanus, A Altınel - Journal of Istanbul Veterinary Sciences, 2017 - dergipark.org.tr
Inherited diseases are caused by recessive alleles proceed from increased inbreeding in
Holstein cattle population. Bovine leucocyte adhesion deficiency (BLAD), deficiency of …

Молекулярно-генетическое тестирование крупного рогатого скота по генам белков молока, гормонов, фермента и наследственных заболеваний

СВ Тюлькин - 2019 - elibrary.ru
Разработаны способы экстракции ДНК из биологического материала от крупного
рогатого скота. Разработаны и усовершенствованы способы проведения ПЦР и ПЦР …

[PDF][PDF] Factors affecting the conception rate of artificial insemination in small cattle dairy farms in an Algerian semi-arid area

C Mouffok, A Allouni, L Semara… - Livest. Res. Rural …, 2019 - researchgate.net
Artificial insemination is beginning to find its place in Algerian dairy cattle farms. The bovine
artificial insemination (AI) assessments for a three-year period in the semi-arid wilaya of Sétif …

Identification of carriers of the mutation causing coagulation factor XI deficiency in Polish Holstein-Friesian cattle

A Gurgul, D Rubiś, E Słota - Journal of Applied Genetics, 2009 - Springer
Factor XI (FXI) deficiency is a hereditary coagulation disorder observed in various
mammalian species. The molecular basis of coagulopathy has been recognized in Holstein …

A genetic predisposition for bovine neonatal pancytopenia is not due to mutations in coagulation factor XI

K Krappmann, R Weikard, S Gerst, C Wolf, C Kühn - The Veterinary Journal, 2011 - Elsevier
Bovine neonatal pancytopenia (BNP) is a newly emerging disease in many European
countries that causes haemorrhagic diathesis and mortality in neonatal calves. This study …