Guidelines for the evaluation and management of status epilepticus

GM Brophy, R Bell, J Claassen, B Alldredge, TP Bleck… - Neurocritical care, 2012 - Springer
Status epilepticus (SE) treatment strategies vary substantially from one institution to another
due to the lack of data to support one treatment over another. To provide guidance for the …

Benzodiazepines in epilepsy: pharmacology and pharmacokinetics

J Riss, J Cloyd, J Gates, S Collins - Acta neurologica …, 2008 - Wiley Online Library
Benzodiazepines (BZDs) remain important agents in the management of epilepsy. They are
drugs of first choice for status epilepticus and seizures associated with post‐anoxic insult …

Treatment of refractory status epilepticus with pentobarbital, propofol, or midazolam: a systematic review

J Claassen, LJ Hirsch, RG Emerson, SA Mayer - Epilepsia, 2002 - Wiley Online Library
Background: New continuous infusion antiepileptic drugs (cIV‐AEDs) offer alternatives to
pentobarbital for the treatment of refractory status epilepticus (RSE). However, no …

Status epilepticus

DH Lowenstein, BK Alldredge - New England Journal of …, 1998 - Mass Medical Soc
A patient in status epilepticus has continuous or rapidly repeating seizures. Although the
danger of this pattern of seizure activity has been recognized since antiquity, our …

Status epilepticus: pathophysiology and management in adults

JWY Chen, CG Wasterlain - The Lancet Neurology, 2006 - thelancet.com
Summary As in Clark and Prout's classic work, we identify three phases of generalised
convulsive status epilepticus, which we call impending, established, and subtle. We review …

Treatment of refractory convulsive status epilepticus: a comprehensive review by the American Epilepsy Society Treatments Committee

DG Vossler, JL Bainbridge, JG Boggs… - Epilepsy …, 2020 - journals.sagepub.com
Purpose: Established tonic–clonic status epilepticus (SE) does not stop in one-third of
patients when treated with an intravenous (IV) benzodiazepine bolus followed by a loading …

Assessing the outcomes in patients with nonconvulsive status epilepticus: nonconvulsive status epilepticus is underdiagnosed, potentially overtreated, and …

PW Kaplan - Journal of Clinical Neurophysiology, 1999 - journals.lww.com
Nonconvulsive status epilepticus (NCSE) is characterized by behavioral or cognitive change
from baseline for at least 30 minutes with EEG evidence of seizures. Categorized into …

Continuous EEG monitoring and midazolam infusion for refractory nonconvulsive status epilepticus

J Claassen, LJ Hirsch, RG Emerson, JE Bates… - Neurology, 2001 - AAN Enterprises
Background: Although cIV-MDZ has emerged as a popular alternative to barbiturate therapy
for refractory status epilepticus (RSE), experience with its use for this indication is limited …

Treatment of refractory status epilepticus with propofol: clinical and pharmacokinetic findings

MM Stecker, TH Kramer, EC Raps, R O'Meeghan… - …, 1998 - Wiley Online Library
Purpose: We compared propofol with high‐dose barbiturates in the treatment of refractory
status epilepticus (RSE) and propose a protocol for the administration of propofol in RSE in …

Propofol and midazolam in the treatment of refractory status epilepticus

A Prasad, BB Worrall, EH Bertram, TP Bleck - Epilepsia, 2001 - Wiley Online Library
Purpose: To explore outcome differences between propofol and midazolam (MDL) therapy
for refractory status epilepticus (RSE). Methods: Retrospective chart review of consecutive …