Analytical and biochemical perspectives of protein O-GlcNAcylation
Protein O-linked β-N-acetylglucosamine (O-GlcNAc) modification (O-GlcNAcylation) is a
unique monosaccharide modification discovered in the early 1980s. With the technological …
unique monosaccharide modification discovered in the early 1980s. With the technological …
Advances in chemical probing of protein O-GlcNAc glycosylation: structural role and molecular mechanisms
A Saha, D Bello, A Fernández-Tejada - Chemical Society Reviews, 2021 - pubs.rsc.org
The addition of O-linked-β-DN-acetylglucosamine (O-GlcNAc) onto serine and threonine
residues of nuclear and cytoplasmic proteins is an abundant, unique post-translational …
residues of nuclear and cytoplasmic proteins is an abundant, unique post-translational …
O-GlcNAcylation determines the translational regulation and phase separation of YTHDF proteins
Y Chen, R Wan, Z Zou, L Lao, G Shao, Y Zheng… - Nature Cell …, 2023 - nature.com
Abstract N 6-methyladenosine (m6A) is the most abundant internal mRNA nucleotide
modification in mammals, regulating critical aspects of cell physiology and differentiation …
modification in mammals, regulating critical aspects of cell physiology and differentiation …
Uncovering post-translational modification-associated protein–protein interactions
In living systems, the chemical space and functional repertoire of proteins are dramatically
expanded through the post-translational modification (PTM) of various amino acid residues …
expanded through the post-translational modification (PTM) of various amino acid residues …
Target protein deglycosylation in living cells by a nanobody-fused split O-GlcNAcase
Abstract O-linked N-acetylglucosamine (O-GlcNAc) is an essential and dynamic post-
translational modification that is presented on thousands of nucleocytoplasmic proteins …
translational modification that is presented on thousands of nucleocytoplasmic proteins …
O-GlcNAcylation and its role in the immune system
YH Chang, CL Weng, KI Lin - Journal of biomedical science, 2020 - Springer
Abstract O-linked-N-acetylglucosaminylation (O-GlcNAcylation) is a type of glycosylation that
occurs when a monosaccharide, O-GlcNAc, is added onto serine or threonine residues of …
occurs when a monosaccharide, O-GlcNAc, is added onto serine or threonine residues of …
Tools for mammalian glycoscience research
ME Griffin, LC Hsieh-Wilson - Cell, 2022 - cell.com
Cellular carbohydrates or glycans are critical mediators of biological function. Their
remarkably diverse structures and varied activities present exciting opportunities for …
remarkably diverse structures and varied activities present exciting opportunities for …
Engineering a proximity-directed O-GlcNAc transferase for selective protein O-GlcNAcylation in cells
DH Ramirez, C Aonbangkhen, HY Wu… - ACS chemical …, 2020 - ACS Publications
O-Linked β-N-acetylglucosamine (O-GlcNAc) is a monosaccharide that plays an essential
role in cellular signaling throughout the nucleocytoplasmic proteome of eukaryotic cells …
role in cellular signaling throughout the nucleocytoplasmic proteome of eukaryotic cells …
Tools, tactics and objectives to interrogate cellular roles of O-GlcNAc in disease
C Fehl, JA Hanover - Nature chemical biology, 2022 - nature.com
The vast array of cell types of multicellular organisms must individually fine-tune their
internal metabolism. One important metabolic and stress regulatory mechanism is the …
internal metabolism. One important metabolic and stress regulatory mechanism is the …
Integration of O-GlcNAc into stress response pathways
KMM Fahie, KN Papanicolaou, NE Zachara - Cells, 2022 - mdpi.com
The modification of nuclear, mitochondrial, and cytosolic proteins by O-linked βN-
acetylglucosamine (O-GlcNAc) has emerged as a dynamic and essential post-translational …
acetylglucosamine (O-GlcNAc) has emerged as a dynamic and essential post-translational …