Aging causes skeletal muscle atrophy, and myofiber loss can be a critical component of this
process. In 1989, Rosenberg emphasized the importance of the loss of skeletal muscle …

Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

Background The aim was to investigate the associations of sarcopenia as defined by
European Working Group on Sarcopenia in Older People (EWGSOP) and Foundation for the …

Background Testosterone supplementation has been shown to increase muscle mass and
strength in healthy older men. The safety and efficacy of testosterone treatment in older men …

Aging is associated with a loss of sex hormone in both men (andropause) and women
(menopause). In men, reductions in testosterone can trigger declines in muscle mass, bone …

Aging in men is accompanied by a progressive, but individually variable decline of serum
testosterone production, more than 20% of healthy men over 60 yr of age presenting with …

Testosterone induces skeletal muscle hypertrophy by multiple mechanisms, including its
effects in modulating the commitment of pluripotent mesenchymal cells. These changes in …

Although testosterone levels and muscle mass decline with age, many older men have
serum testosterone level in the normal range, leading to speculation about whether older …

ContextHormone administration to elderly individuals can increase lean body mass (LBM)
and decrease fat, but interactive effects of growth hormone (GH) and sex steroids and their …

Context: Findings of studies of testosterone's effects on muscle strength and physical
function in older men have been inconsistent; its effects on muscle power and fatigability …