Saffron (Crocus sativus L.): A Source of Nutrients for Health and for the Treatment of Neuropsychiatric and Age-Related Diseases

A El Midaoui, I Ghzaiel, D Vervandier-Fasseur, M Ksila… - Nutrients, 2022 - mdpi.com
Saffron (Crocus sativus L.) is a medicinal plant, originally cultivated in the East and Middle
East, and later in some Mediterranean countries. Saffron is obtained from the stigmas of the …

The role of Safranal and saffron stigma extracts in oxidative stress, diseases and photoaging: A systematic review

S Nanda, K Madan - Heliyon, 2021 - cell.com
Reactive oxygen species (ROS) are produced as a result of various environmental factors
and cellular metabolism reactions creating oxidative stress. The reversible oxidative …

Active constituents of saffron (Crocus sativus L.) and their prospects in treating neurodegenerative diseases

W Yang, X Qiu, Q Wu, F Chang… - Experimental and …, 2023 - spandidos-publications.com
Crocus sativus L.(saffron) is widely used as a traditional spice for flavoring, coloring and
medicinal purposes. As a traditional Chinese herb, saffron promotes blood circulation …

[HTML][HTML] Neuroprotective potency of saffron against neuropsychiatric diseases, neurodegenerative diseases, and other brain disorders: from bench to bedside

Y Bian, C Zhao, SMY Lee - Frontiers in Pharmacology, 2020 - frontiersin.org
The increasing morbidity rates of brain disorders and conditions such as anxiety,
depression, Alzheimer's disease, and Parkinson's disease have become a severe problem …

Delineation of neuroprotective effects and possible benefits of antioxidantstherapy for the treatment of Alzheimer's diseases by targeting mitochondrial-derived …

V Walia, D Kaushik, V Mittal, K Kumar, R Verma… - Molecular …, 2021 - Springer
Alzheimer's disease (AD) is considered the sixth leading cause of death in elderly patients
and is characterized by progressive neuronal degeneration and impairment in memory …

Role of phytochemicals as nutraceuticals for cognitive functions affected in ageing

MJR Howes, NSL Perry… - British journal of …, 2020 - Wiley Online Library
Cognitive decline can occur with normal ageing and in age‐related brain disorders, such as
mild cognitive impairment and dementia, including Alzheimer's disease, with limited …

[HTML][HTML] Pharmacological effects of Safranal: An updated review

D Esmaealzadeh, AAM Ghalibaf, MS Rad… - Iranian journal of …, 2023 - ncbi.nlm.nih.gov
Safranal (a monoterpene aldehyde) is the major volatile component of saffron which is
responsible for the saffron unique odor. Several studies have shown the pharmacological …

Safranal, an active ingredient of saffron, attenuates cognitive deficits in amyloid β-induced rat model of Alzheimer's disease: underlying mechanisms

T Baluchnejadmojarad, SM Mohamadi-Zarch… - Metabolic brain …, 2019 - Springer
Alzheimer's disease (AD) is the most prevalent neurodegenerative amyloid disorder with
progressive deterioration of cognitive and memory skills. Despite many efforts, no decisive …

Research progress of natural products and their derivatives against Alzheimer's disease

JY Liu, HY Guo, ZS Quan, QK Shen… - Journal of enzyme …, 2023 - Taylor & Francis
Abstract Alzheimer's disease (AD), a persistent neurological dysfunction, has an increasing
prevalence with the aging of the world and seriously threatens the health of the elderly …

Safranal alleviated OVA-induced asthma model and inhibits mast cell activation

P Lertnimitphun, W Zhang, W Fu, B Yang… - Frontiers in …, 2021 - frontiersin.org
Introduction Asthma is a chronic and recurring airway disease, which related to mast cell
activation. Many compounds derived from Chinese herbal medicine has promising effects …