Immunoglobulin (IgG) glycosylation is a complex enzymatically controlled process, essential
for the structure and function of IgG. IgG glycome is relatively stable in the state of …

Ovarian cancer (OC) causes significant morbidity and mortality as neither detection nor
screening of OC is currently feasible at an early stage. Difficulty to promptly diagnose OC in …

Glycoproteins are decorated with complex glycans for protein functions. However, regulation
mechanisms of complex glycan biosynthesis are largely unclear. Here we found that …

N-glycosylation is an abundant post-translational modification of most cell-surface proteins.
N-glycans play a crucial role in cellular functions like protein folding, protein localization, cell …

N-glycosylation is a frequent modification of proteins, essential for all domains of life. N-
glycan biosynthesis is a dynamic, complex, non-templated process, wherein specific …

Glycosylation is the most ubiquitous post-translational modification in eukaryotes. N-glycan
is attached to nascent glycoproteins and is processed and matured by various glycosidases …

Epithelial ovarian cancer is one of the most fatal gynecological malignancies in adult
women. As studies on protein N‐glycosylation have extensively reported aberrant patterns …

Transforming growth factor (TGF)‑β1 is a key cytokine affecting the pathogenesis and
progression of cervical cancer. Tumor‑derived exosomes contain microRNAs …

Establishing causal relationship between epigenetic marks and gene transcription requires
molecular tools, which can precisely modify specific genomic regions. Here, we present a …

Aberrant glycan epitopes are a classic hallmark of malignant transformation, yet their full
clinical potential in cancer diagnostics and therapeutics is yet to be realized. This is partly …