The role of cytokines in Leishmania amazonensis experimental infection has not been as
well studied as in Leishmania major infection model. Here we investigated the role of …

Leishmania major cutaneous leishmaniasis (CL) lesions are characterized by an intense
process of parasite destruction and antigen processing that could limit microscopic …

Contact with Leishmania leads to a decreases in mononuclear phagocyte adherence to
connective tissue. In this work, we studied the early stages of bond formation between VLA4 …

Diseases such as leishmaniases are important causes of morbidity and mortality in Brazil,
and their diagnoses need to be improved. The use of monoclonal antibodies has ensured …

Domestic dogs are considered to be the main reservoirs of zoonotic visceral leishmaniasis.
In this work, we evaluated a protocol to induce Leishmania infantum/Leishmania chagasi …

Leishmania chagasi is the causative agent of visceral leishmaniasis in both humans and
dogs in the New World. The dog is the main domestic reservoir and its infection displays …

Background In this paper we study the distribution of leukocyte populations and of cytokine-
producing cells in the spleen of a patient with visceral leishmaniasis resistant to clinical …

The sensitivity of diagnostic methods for visceral leishmaniasis (VL) decreases because of
the low number of parasites and antibody amounts in asymptomatic healthy donors who are …

Immunomagnetic Separation (IMS) assay has been used for isolation of viable whole
organisms. The objective of our work is to produce anti-Leishmania magnetic beads and to …

Background The in situ detection of parasite antigens in tissue sections by
immunohistochemistry (IHC) is a diagnostic alternative for human American tegumentary …