Uncovering the genetics and physiology behind optic neuritis

I Del Negro, G Pauletto, L Verriello, L Spadea, C Salati… - Genes, 2023 - mdpi.com
Optic neuritis (ON) is an inflammatory condition affecting the optic nerve, leading to vision
impairment and potential vision loss. This manuscript aims to provide a comprehensive …

Matrix metalloproteinases (MMPs) family gene polymorphisms and the risk of multiple sclerosis: systematic review and meta-analysis

M Mohammadhosayni, A Khosrojerdi, K Lorian… - BMC neurology, 2020 - Springer
Background Several studies have reported the association between polymorphisms in
Matrix metalloproteinases (MMPs) gene family and risk of Multiple sclerosis (MS). However …

Genome-Wide Expression Profile in People with Optic Neuritis Associated with Multiple Sclerosis

M Habek, A Blazekovic, K Gotovac Jercic, N Pivac… - Biomedicines, 2023 - mdpi.com
The aim of this study was to perform a genome-wide expression analysis of whole-blood
samples from people with optic neuritis (ON) and to determine differentially expressed …

Does CETP rs5882, rs708272, SIRT1 rs12778366, FGFR2 rs2981582, STAT3 rs744166, VEGFA rs833068, IL6 rs1800795 polymorphisms play a role in optic …

G Gedvilaite, A Vilkeviciute, L Kriauciuniene… - Ophthalmic …, 2019 - Taylor & Francis
Objectives: Optic neuritis (ON) is defined as inflammation of the optic nerve, which is mostly
idiopathic. However, it can be associated with various causes (demyelinating lesions …

Optic Neuritis: The Influence of Gene Polymorphisms and Serum Levels of STAT4 (rs10181656, rs7574865, rs7601754, rs10168266)

G Gedvilaite, M Duseikaitė, G Dubinskaite… - Journal of Clinical …, 2023 - mdpi.com
The aim of the study was to evaluate the associations of STAT4 (rs10181656, rs7574865,
rs7601754, rs10168266) gene polymorphisms and STAT4 serum level in patients with optic …

Otolaryngologic symptoms in multiple sclerosis: a review

M Ralli, A Di Stadio, IC Visconti, FY Russo… - The International …, 2018 - iris.uniroma1.it
Many symptoms of multiple sclerosis may affect the ear, nose and throat. The most common
otolaryngologic symptoms of multiple sclerosis are speech disorders, followed by sleep …

Association of RAGE rs1800624 and rs1800625 gene polymorphisms with predisposition to optic neuritis and optic neuritis together with multiple sclerosis

G Kolonaite, A Vilkeviciute, L Kriauciuniene… - Ophthalmic …, 2021 - Taylor & Francis
Optic neuritis (ON) is demyelinating acute inflammatory disease which affects the optic
nerve. ON is classified as a typical (demyelinating) or an atypical (idiopathic). Patients often …

Associations between IL1RAP rs4624606, IL1RL1 rs1041973, IL-6 rs1800795, and HTRA1 rs11200638 gene polymorphisms and development of optic neuritis with …

V Stonys, M Lindžiūtė, A Vilkevičiūtė… - Ophthalmic …, 2020 - Taylor & Francis
Background Optic neuritis (ON) and multiple sclerosis (MS) are complex diseases with
multifactorial pathogenesis. The role of genetic factors in the development of these diseases …

Association of VEGFA, TIMP-3, and IL-6 gene polymorphisms with predisposition to optic neuritis and optic neuritis with multiple sclerosis

V Punyte, A Vilkeviciute, G Gedvilaite… - Ophthalmic …, 2021 - Taylor & Francis
Background The etiology of the inflammatory ON is multifactorial. Much attention is paid to
the inflammatory and immune processes that are likely to contribute to the demyelination …

Povezanost optičkog neuritisa i multiple skleroze u Splitsko-dalmatinskoj županiji

I Jurić - 2023 - zir.nsk.hr
Sažetak Cilj istraživanja: Cilj ovog retrospektivnog istraživanje je odrediti učestalost akutnog
monosimptomaskog optičkog neuritisa i ispitati povezanost akutne epizode …