RNA four-way junction (4WJ) for spontaneous cancer-targeting, effective tumor-regression, metastasis suppression, fast renal excretion and undetectable toxicity
The field of RNA therapeutics has been emerging as the third milestone in pharmaceutical
drug development. RNA nanoparticles have displayed motile and deformable properties to …
drug development. RNA nanoparticles have displayed motile and deformable properties to …
Cracking the Code: Enhancing Molecular Tools for Progress in Nanobiotechnology
Nature continually refines its processes for optimal efficiency, especially within biological
systems. This article explores the collaborative efforts of researchers worldwide, aiming to …
systems. This article explores the collaborative efforts of researchers worldwide, aiming to …
[HTML][HTML] RNA nanotechnology on the horizon: Self-assembly, chemical modifications, and functional applications
JM Stewart - Current Opinion in Chemical Biology, 2024 - Elsevier
RNA nanotechnology harnesses the unique chemical and structural properties of RNA to
build nanoassemblies and supramolecular structures with dynamic and functional …
build nanoassemblies and supramolecular structures with dynamic and functional …
RNA Nanotechnology for Codelivering High-Payload Nucleoside Analogs to Cancer with a Synergetic Effect
Nucleoside analogs are potent inhibitors for cancer treatment, but the main obstacles to their
application in humans are their toxicity, nonspecificity, and lack of targeted delivery tools …
application in humans are their toxicity, nonspecificity, and lack of targeted delivery tools …
[PDF][PDF] Conversion of Chemical Drugs into Targeting Ligands on RNA Nanoparticles and Assessing Payload Stoichiometry for Optimal Biodistribution in Cancer …
Active targeting-mediated nanodelivery takes advantages of ligand-receptor specificity to
avoid non-specific distribution, holding great promise for the treatment of a spectrum of …
avoid non-specific distribution, holding great promise for the treatment of a spectrum of …