Human genetic and immunological determinants of critical COVID-19 pneumonia
Q Zhang, P Bastard, A Cobat, JL Casanova - Nature, 2022 - nature.com
SARS-CoV-2 infection is benign in most individuals but, in around 10% of cases, it triggers
hypoxaemic COVID-19 pneumonia, which leads to critical illness in around 3% of cases …
hypoxaemic COVID-19 pneumonia, which leads to critical illness in around 3% of cases …
Post-acute sequelae of COVID-19: A metabolic perspective
The SARS-CoV-2 pandemic continues to rage around the world. At the same time, despite
strong public health measures and high vaccination rates in some countries, a post-COVID …
strong public health measures and high vaccination rates in some countries, a post-COVID …
Identifying who has long COVID in the USA: a machine learning approach using N3C data
Background Post-acute sequelae of SARS-CoV-2 infection, known as long COVID, have
severely affected recovery from the COVID-19 pandemic for patients and society alike. Long …
severely affected recovery from the COVID-19 pandemic for patients and society alike. Long …
Association between immune dysfunction and COVID-19 breakthrough infection after SARS-CoV-2 vaccination in the US
Importance Persons with immune dysfunction have a higher risk for severe COVID-19
outcomes. However, these patients were largely excluded from SARS-CoV-2 vaccine …
outcomes. However, these patients were largely excluded from SARS-CoV-2 vaccine …
Associations between HIV infection and clinical spectrum of COVID-19: a population level analysis based on US National COVID Cohort Collaborative (N3C) data
Background Evidence of whether people living with HIV are at elevated risk of adverse
COVID-19 outcomes is inconclusive. We aimed to investigate this association using the …
COVID-19 outcomes is inconclusive. We aimed to investigate this association using the …
Risk factors of severe COVID-19: a review of host, viral and environmental factors
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …
asymptomatic infections to severe disease and death. Understanding the risk factors of …
The pathogenesis of coronavirus-19 disease
AC Borczuk, RK Yantiss - Journal of biomedical science, 2022 - Springer
Severe acute respiratory syndrome-associated coronavirus-2 (SARS-CoV-2) is the causal
agent of coronavirus disease-2019 (COVID-19), a systemic illness characterized by variably …
agent of coronavirus disease-2019 (COVID-19), a systemic illness characterized by variably …
Ethnic inequalities in COVID-19 infection, hospitalisation, intensive care admission, and death: a global systematic review and meta-analysis of over 200 million study …
Background COVID-19 has exacerbated existing ethnic inequalities in health. Little is known
about whether inequalities in severe disease and deaths, observed globally among …
about whether inequalities in severe disease and deaths, observed globally among …
Dissecting human population variation in single-cell responses to SARS-CoV-2
Humans display substantial interindividual clinical variability after SARS-CoV-2 infection,–,
the genetic and immunological basis of which has begun to be deciphered. However, the …
the genetic and immunological basis of which has begun to be deciphered. However, the …
Assessment of clinical outcomes among children and adolescents hospitalized with COVID-19 in 6 sub-Saharan African countries
JB Nachega, NA Sam-Agudu, RN Machekano… - JAMA …, 2022 - jamanetwork.com
Importance Little is known about COVID-19 outcomes among children and adolescents in
sub-Saharan Africa, where preexisting comorbidities are prevalent. Objective To assess the …
sub-Saharan Africa, where preexisting comorbidities are prevalent. Objective To assess the …