Placental pathology in early-onset and late-onset fetal growth restriction

W Mifsud, NJ Sebire - Fetal diagnosis and therapy, 2014 - karger.com
Several histopathological features are found more frequently in placentas from pregnancies
complicated by fetal growth restriction (FGR), including villous infarction, maternal vascular …

MicroRNAs in human placental development and pregnancy complications

G Fu, J Brkić, H Hayder, C Peng - International journal of molecular …, 2013 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs, which function as critical
posttranscriptional regulators of gene expression by promoting mRNA degradation and …

Interactions between trophoblast cells and the maternal and fetal circulation in the mouse placenta

SL Adamson, Y Lu, KJ Whiteley, D Holmyard… - Developmental …, 2002 - Elsevier
Mammalian embryos have an intimate relationship with their mothers, particularly with the
placental vasculature from which embryos obtain nutrients essential for growth. It is an …

Angiogenesis and vasculogenesis in pregnancy

M Zygmunt, F Herr, K Münstedt, U Lang… - European Journal of …, 2003 - Elsevier
An adequate nutrient and substrate supply is essential for normal intrauterine development
of the fetus. Disturbances in uterine blood supply are associated with higher perinatal …

Placental insufficiency and its consequences

R Gagnon - European Journal of Obstetrics & Gynecology and …, 2003 - Elsevier
Placental insufficiency is a process leading to progressive deterioration in placental function
and a decrease in transplacental transfer of oxygen and nutrients to the fetus. The resulting …

Maternal medicine: Morphometric placental villous and vascular abnormalities in early‐and late‐onset pre‐eclampsia with and without fetal growth restriction

M Egbor, T Ansari, N Morris, CJ Green… - … Journal of Obstetrics …, 2006 - Wiley Online Library
Objective To evaluate placental morphology in pregnancies complicated by early‐and late‐
onset pre‐eclampsia (PET) with and without fetal growth restriction (FGR) using …

Development of the human placenta and fetal heart: synergic or independent?

GJ Burton, E Jauniaux - Frontiers in physiology, 2018 - frontiersin.org
The placenta is the largest fetal organ, and toward the end of pregnancy the umbilical
circulation receives at least 40% of the biventricular cardiac output. It is not surprising …

Development of the placental villous tree and its consequences for fetal growth

J Kingdom, B Huppertz, G Seaward… - European Journal of …, 2000 - Elsevier
Co-ordinated development of the fetal villous tree of the placenta is necessary for continued
fetal growth and well-being. Before fetal viability, blood vessel development within the …

Plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated prior to the clinical diagnosis of pre-eclampsia

T Chaiworapongsa, R Romero, YM Kim… - The journal of …, 2005 - Taylor & Francis
Objective: Accumulating evidence suggests that the balance between vascular endothelial
growth factor (VEGF), placental growth factor (PlGF), and their receptors is important for …

Aspects of human fetoplacental vasculogenesis and angiogenesis. III. Changes in complicated pregnancies

TM Mayhew, DS Charnock-Jones, P Kaufmann - Placenta, 2004 - Elsevier
Patterns of fetoplacental angiogenesis vary not only during the course of a normal
pregnancy but also in certain pregnancy pathologies. Here, we review some of the …