At the frontline of the host defence response, neutrophil antimicrobial functions have
adapted to combat infections and injuries of different origins and magnitude. The release of …

Neutrophils are the most abundant leukocytes in the circulation, and have been regarded as
first line of defense in the innate arm of the immune system. They capture and destroy …

Emerging data indicate that complement and neutrophils contribute to the maladaptive
immune response that fuels hyperinflammation and thrombotic microangiopathy, thereby …

Intercellular communication is a critical process that ensures cooperation between distinct
cell types and maintains homeostasis. EVs, which were initially described as cellular debris …

The transcription factor NF-κB is a central mediator of inflammation with multiple links to
thrombotic processes. In this review, we focus on the role of NF-κB signaling in cell types …

Recent studies have demonstrated a role of neutrophils in both venous and arterial
thrombosis. A key prothrombotic feature of neutrophils is their ability to release web-like …

Neutrophil extracellular trap (NET) formation, first described in 2004 as a previously
unknown strategy of neutrophils to fight microbes, has attracted an increasing interest in the …

The production of neutrophil extracellular traps (NETs) is a process that enables neutrophils
to help catch and kill bacteria. However, increasing evidence suggests that this process …

Neutrophil extracellular traps (NETs) have recently emerged as a newly recognized
contributor to venous and arterial thrombosis. These strands of DNA extruded by activated or …

Neutrophil extracellular traps (NETs; webs of DNA coated in antimicrobial proteins) are
released into the vasculature during sepsis where they contribute to host defense, but also …