Natural behavior is the language of the brain

CT Miller, D Gire, K Hoke, AC Huk, D Kelley… - Current Biology, 2022 - cell.com
The breadth and complexity of natural behaviors inspires awe. Understanding how our
perceptions, actions, and internal thoughts arise from evolved circuits in the brain has …

A review of gaze entropy as a measure of visual scanning efficiency

B Shiferaw, L Downey, D Crewther - Neuroscience & Biobehavioral …, 2019 - Elsevier
While the concept of entropy has been applied to gaze analysis, it is unclear what aspects of
visual scanning it measures. In this review, we first outline gaze control as a complex system …

Viewpoints: Approaches to defining and investigating fear

D Mobbs, R Adolphs, MS Fanselow, LF Barrett… - Nature …, 2019 - nature.com
There is disagreement on how best to define and investigate fear. Nature Neuroscience
asked Dean Mobbs to lead experts from the fields of human and animal affective …

Mouse prefrontal cortex represents learned rules for categorization

S Reinert, M Hübener, T Bonhoeffer, PM Goltstein - Nature, 2021 - nature.com
The ability to categorize sensory stimuli is crucial for an animal's survival in a complex
environment. Memorizing categories instead of individual exemplars enables greater …

Dynamic influences on the neural encoding of social valence

N Padilla-Coreano, KM Tye… - Nature Reviews …, 2022 - nature.com
Social signals can serve as potent emotional triggers with powerful impacts on processes
from cognition to valence processing. How are social signals dynamically and flexibly …

The mouse prefrontal cortex: Unity in diversity

P Le Merre, S Ährlund-Richter, M Carlén - Neuron, 2021 - cell.com
The prefrontal cortex (PFC) is considered to constitute the highest stage of neural integration
and to be devoted to representation and production of actions. Studies in primates have laid …

Distinct circuits in anterior cingulate cortex encode safety assessment and mediate flexibility of fear reactions

K Wu, D Wang, Y Wang, P Tang, X Li, Y Pan, HW Tao… - Neuron, 2023 - cell.com
Safety assessment and threat evaluation are crucial for animals to live and survive in the
wilderness. However, neural circuits underlying safety assessment and their transformation …

Mixed selectivity: Cellular computations for complexity

KM Tye, EK Miller, FH Taschbach, MK Benna, M Rigotti… - Neuron, 2024 - cell.com
The property of mixed selectivity has been discussed at a computational level and offers a
strategy to maximize computational power by adding versatility to the functional role of each …

Distinct prefrontal top-down circuits differentially modulate sensorimotor behavior

R Huda, GO Sipe, V Breton-Provencher… - Nature …, 2020 - nature.com
Sensorimotor behaviors require processing of behaviorally relevant sensory cues and the
ability to select appropriate responses from a vast behavioral repertoire. Modulation by the …

A specialized spinal circuit for command amplification and directionality during escape behavior

NN Guan, L Xu, T Zhang, CX Huang… - Proceedings of the …, 2021 - National Acad Sciences
In vertebrates, action selection often involves higher cognition entailing an evaluative
process. However, urgent tasks, such as defensive escape, require an immediate …