The eye is a metabolically active structure, constantly exposed to solar radiations making its
structure vulnerable to the high burden of reactive oxygen species (ROS), presenting many …

The human eye, the highly specialized organ of vision, is greatly influenced by oxidants of
endogenous and exogenous origin. Oxidative stress affects all structures of the human eye …

Oxidative stress (OS) refers to an imbalance between free radicals (FRs), namely highly
reactive molecules normally generated in our body by several pathways, and intrinsic …

Eye drops are ophthalmic formulations routinely used to treat dry eye. However, the low
ocular bioavailability is an obvious drawback of eye drops owing to short ocular retention …

Vision impairment has devastating consequences for the quality of human life. The cells and
tissues associated with the visual process must function throughout one's life span and …

Dry eye disease (DED) is a multifactorial disease, and oxidative stress plays a crucial role in
its pathogenesis. Recently, multiple studies have shown that upregulation of autophagy can …

Eye health is crucial, and the onset of diseases can reduce vision and affect the quality of life
of patients. The main causes of progressive and irreversible vision loss include various …

Dry eye disease (DED), a complex ocular surface disease with a high prevalence rate, is
associated with corneal injury, excess oxidative stress and inflammation. Current therapeutic …

Dry eye disease (DED) is a multifactorial condition affecting the ocular surface. It is
characterized by loss of tear film homeostasis and accompanied by ocular symptoms that …

All proteins have the inherent ability to undergo transformation from their native structure to a
β sheet rich fibrillar structure, called amyloid when subjected to specific conditions. Proteins …