Pain modulated by Bothrops snake venoms: Mechanisms of nociceptive signaling and therapeutic perspectives

J dos Santos Cavalcante, FAN Júnior, RJB Jorge… - Toxicon, 2021 - Elsevier
Snake venoms are substances mostly composed by proteins and peptides with high
biological activity. Local and systemic effects culminate in clinical manifestations induced by …

Potential metabolites of Arecaceae family for the natural anti-osteoarthritis medicine: A review

A Sartinah, I Nugrahani, S Ibrahim, K Anggadiredja - Heliyon, 2022 - cell.com
Osteoarthritis (OA) is a chronic inflammatory disorder of the joints caused by fluid and
cartilage matrix component reduction. This disease results in symptoms of pain, deformity …

A fingerprint of plasma proteome alteration after local tissue damage induced by Bothrops leucurus snake venom in mice

J dos Santos Cavalcante, CAS de Almeida… - Journal of …, 2022 - Elsevier
Bothrops spp. is responsible for about 70% of snakebites in Brazil, causing a diverse and
complex pathophysiological condition. Bothrops leucurus is the main species of medical …

Type I-like metalloproteinase in the venom of the West African saw-scaled carpet viper (Echis ocellatus) has anti-trypanosomal activity against African trypanosomes

A Ilu, MA Chia, TR Cataldi, CA Labate, GU Ebiloma… - Toxicon, 2023 - Elsevier
African trypanosomiasis is an infectious disease caused by hemoparasites of the genus
Trypanosoma and remains a major health problem in Africa-killing around 4000 people and …

Review of the Mechanisms of snake venom induced pain: It's all about location, location, location

VG Nielsen, MT Wagner - International journal of molecular sciences, 2022 - mdpi.com
Pain—acute, chronic and debilitating—is the most feared neurotoxicity resulting from a
survivable venomous snake bite. The purpose of this review is to present in a novel …

[HTML][HTML] Anti-inflammatory, healing and antiophidic potential of Jatropha mollissima (Pohl) Baill.(Euphorbiaceae): From popular use to pharmaceutical formulation in …

JGR Passos, JAS Gomes, JB Xavier-Santos… - Biomedicine & …, 2024 - Elsevier
Abstract Jatropha mollissima (Pohl) Baill.(Euphorbiaceae) is widely used in traditional
medicine to treat inflammatory disorders. So, a topical gel containing the hydroethanolic …

Ayahuasca and its major component harmine promote antinociceptive effects in mouse models of acute and chronic pain

PSS Lauria, J de Medeiros Gomes, LS Abreu… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Ayahuasca (AYA) is a psychedelic brew used in religious
ceremonies. It is broadly used as a sacred medicine for treating several ailments, including …

Development of chicken egg yolk antibodies (IgY) against venom of cobra (Naja naja) and krait (Bungarus caeruleus) and a study on its neutralization potential

G Gopal, M Antonysamy, S Visaga Ambi… - Toxin Reviews, 2024 - Taylor & Francis
Abstract The Big Four snakes are the leading causes of snakebite mortality in India. Among
them, The Indian spectacled cobra (Naja naja) and common krait (Bungarus caeruleus) …

[HTML][HTML] Antivenom Administration After Rattlesnake Envenoming in Arizona Does Not Directly Diminish Pain

VG Nielsen, DL Stratton, TM Hoelscher, HL Nakamura… - Toxins, 2024 - mdpi.com
The onset, progression, and severity of pain following rattlesnake envenomation are highly
variable between patients. Pain can be severe and persistent, seemingly refractory to opioid …

Análise do potencial inibitório do ácido clorogênico e do ácido rosmarínico frente aos efeitos da peçonha da serpente Bothrops Leucurus Wagler (1824)

DP Silva - 2022 - bdtd.ibict.br
Os acidentes ofídicos representam um sério problema de saúde pública em países
tropicais. A serpente Bothrops leucurus é uma das principais responsáveis pelos acidentes …