Dried blood spots (DBS) typically consist in the deposition of small volumes of capillary
blood onto dedicated paper cards. Comparatively to whole blood or plasma samples, their …

About a century after its first described application by Ivar Bang, the potential of sampling via
dried blood spots (DBS) as an alternative for classical venous blood sampling is …

This two-sequence, three-period crossover study is the first pharmacokinetic (PK) study to
compare all three innovator formulations of tacrolimus (twice-daily immediate-release …

The purpose of this study was to determine the intrapatient (within the same patient)
variability of tacrolimus in adherent patients. Daily tacrolimus trough levels were obtained at …

In the present study, a new type of mass spectrometer combining a quadrupole mass filter, a
higher collision dissociation (HCD) cell and an Orbitrap detector, was evaluated for the …

Opioids are well known, widely used painkillers. Increased stability of opioids in the dried
blood spot (DBS) matrix compared to blood/plasma has been described. Other benefits …

Dried blood spot (DBS) sampling and DBS analysis have increasingly received attention
during recent years. Furthermore, a substantial number of DBS methods has recently …

Dried blood spot (DBS) sampling, the collection of whole blood samples on paper, is an
emerging technique used for bioanalytical methods. Several analytical challenges, such as …

A method for the simultaneous determination of 11 illicit drugs, using the dried blood spot
(DBS) sampling technique combined with the UPLC–MS/MS technology was developed to …

Aim: Large interindividual variability in morphine disposition could contribute to
unpredictable variability in morphine analgesia and adverse events. Caucasian children …