Millions of people are suffering from Long COVID or post-acute sequelae of COVID-19
(PASC). Several biological factors have emerged as potential drivers of PASC pathology …

The germinal centre (GC) response is critical for the generation of affinity-matured plasma
cells and memory B cells capable of mediating long-term protective immunity …

Background & Aims The coronavirus disease 2019 (COVID-19) pandemic has affected
populations, societies, and lives for more than 2 years. Long-term sequelae of COVID-19 …

Some patients hospitalized with acute COVID-19 suffer respiratory symptoms that persist for
many months. We delineated the immune-proteomic landscape in the airways and …

Most studies of adaptive immunity to SARS-CoV-2 infection focus on peripheral blood, which
may not fully reflect immune responses at the site of infection. Using samples from 110 …

Long-term immunological memory to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is crucial for the development of population-level immunity, which is the aim …

Summary In this Personal View, we discuss current knowledge on SARS-CoV-2 RNA or
antigen persistence in children infected with SARS-CoV-2. Based on the evidence that the …

The PD-1 pathway is a cornerstone in immune regulation. While the PD-1 pathway has
received considerable attention for its role in contributing to the maintenance of T cell …

Dendritic cells (DCs) play critical roles in activating innate immune cells and initiating
adaptive immune responses. The functions of DCs were originally obscured by their overlap …

Influenza is a deadly and costly infectious disease, even during flu seasons when an
effective vaccine has been developed. To improve vaccines against respiratory viruses, a …