Designing bioresponsive nanomaterials for intracellular self-assembly
Supramolecular assemblies are essential components of living organisms. Cellular
scaffolds, such as the cytoskeleton or the cell membrane, are formed via secondary …
scaffolds, such as the cytoskeleton or the cell membrane, are formed via secondary …
Exosomes in angiogenesis and anti-angiogenic therapy in cancers
W Olejarz, G Kubiak-Tomaszewska… - International Journal of …, 2020 - mdpi.com
Angiogenesis is the process through which new blood vessels are formed from pre-existing
ones. Exosomes are involved in angiogenesis in cancer progression by transporting …
ones. Exosomes are involved in angiogenesis in cancer progression by transporting …
The genetics of antithrombin
Antithrombin is a key endogenous anticoagulant whose deficiency constitutes a strong risk
factor for thrombosis. The study of antithrombin deficiency has generated excellent, and in …
factor for thrombosis. The study of antithrombin deficiency has generated excellent, and in …
Glioblastoma ablates pericytes antitumor immune function through aberrant up-regulation of chaperone-mediated autophagy
R Valdor, D García-Bernal… - Proceedings of the …, 2019 - National Acad Sciences
The contractile perivascular cells, pericytes (PC), are hijacked by glioblastoma (GB) to
facilitate tumor progression. PC's protumorigenic function requires direct interaction with …
facilitate tumor progression. PC's protumorigenic function requires direct interaction with …
Hemostatic biomarkers in cancer progression
A Falanga, M Marchetti - Thrombosis research, 2018 - Elsevier
Malignant disease is characterized by a hemostatic imbalance, usually shifted towards a
procoagulant direction, and a high incidence of thrombotic complications. The mechanisms …
procoagulant direction, and a high incidence of thrombotic complications. The mechanisms …
Plant serpins: Potential inhibitors of serine and cysteine proteases with multiple functions
MM Ferreira, AS Santos, AS Santos, M Zugaib… - Plants, 2023 - mdpi.com
Plant serpins are a superfamily of protein inhibitors that have been continuously studied in
different species and have great biotechnological potential. However, despite ongoing …
different species and have great biotechnological potential. However, despite ongoing …
Advancements and Challenges of Nanostructured Lipid Carriers for Wound Healing Applications
The current treatments for wound healing still exhibit drawbacks due to limited availability at
the action sites, susceptibility to degradation, and immediate drug release, all of which are …
the action sites, susceptibility to degradation, and immediate drug release, all of which are …
Two dimensional-difference in gel electrophoresis (2D-DIGE) proteomic approach for the identification of biomarkers in endometrial cancer serum
Simple Summary Endometrial cancer is the most common gynecologic malignancy arising
from the endometrium. Identification of serum biomarkers could be beneficial for its early …
from the endometrium. Identification of serum biomarkers could be beneficial for its early …
A novel nanoproteomic approach for the identification of molecular targets associated with thyroid tumors
M García-Vence, MP Chantada-Vázquez… - Nanomaterials, 2020 - mdpi.com
A thyroid nodule is the most common presentation of thyroid cancer; thus, it is extremely
important to differentiate benign from malignant nodules. Within malignant lesions …
important to differentiate benign from malignant nodules. Within malignant lesions …
Serpinc1 acts as a tumor suppressor in hepatocellular carcinoma through inducing apoptosis and blocking macrophage polarization in an ubiquitin-proteasome …
D Xu, J Wu, L Dong, W Luo, L Li, D Tang, J Liu - Frontiers in Oncology, 2021 - frontiersin.org
Serpinc1 is a serine protease inhibitor in the coagulation cascade, but its role in tumor
biology remains obscure. Here, we report an unexpected role of serpinc1 in suppression of …
biology remains obscure. Here, we report an unexpected role of serpinc1 in suppression of …