MRI-guided prostate adaptive radiotherapy–A systematic review

AJ McPartlin, XA Li, LE Kershaw, U Heide… - Radiotherapy and …, 2016 - Elsevier
Dose escalated radiotherapy improves outcomes for men with prostate cancer. A plateau for
benefit from dose escalation using EBRT may not have been reached for some patients with …

Stereotactic body radiotherapy: hitting harder, faster, and smarter in high-risk prostate cancer

RJM Correa, A Loblaw - Frontiers in Oncology, 2022 - frontiersin.org
Stereotactic body radiotherapy (SBRT) is a technologically sophisticated form of
radiotherapy that holds significant potential to effectively treat high-risk prostate cancer …

Two-fraction stereotactic ablative radiotherapy with simultaneous boost to MRI-defined dominant intra-prostatic lesion–Results from the 2SMART phase 2 trial

WL Ong, P Cheung, H Chung, W Chu, J Detsky… - Radiotherapy and …, 2023 - Elsevier
Purpose This is the first report of the 2SMART Phase II trial evaluating the safety of two-
fraction stereotactic ablative radiotherapy (SABR) with focal boost to magnetic resonance …

Dose-escalation of five-fraction SABR in prostate cancer: Toxicity comparison of two prospective trials

HB Musunuru, H Quon, M Davidson, P Cheung… - Radiotherapy and …, 2016 - Elsevier
Purpose To compare biochemical outcome and toxicities of two prospective 5-fraction
stereotactic ablative radiotherapy (SABR) studies in prostate cancer. Materials and methods …

Two StereoTactic ablative radiotherapy treatments for localized prostate cancer (2STAR): Results from a prospective clinical trial

Y Alayed, P Cheung, W Chu, H Chung… - Radiotherapy and …, 2019 - Elsevier
Purpose Ultrahypofractionation is appealing for prostate cancer (PCa) due to low α/β, and
increasing the dose per fraction could improve the therapeutic index. Here we report the …

Dosimetric correlates of toxicities and quality of life following two-fraction stereotactic ablative radiotherapy (SABR) for prostate cancer

WL Ong, M Davidson, P Cheung, H Chung… - Radiotherapy and …, 2023 - Elsevier
Purpose There is no evidence-based data to guide dose constraints in two-fraction prostate
stereotactic ablative radiotherapy (SABR). Using individual patient-data from two …

Stereotactic body radiation therapy with optional focal lesion ablative microboost in prostate cancer: Topical review and multicenter consensus

C Draulans, R De Roover, UA van der Heide… - Radiotherapy and …, 2019 - Elsevier
Stereotactic body radiotherapy (SBRT) for prostate cancer (PCa) is gaining interest by the
recent publication of the first phase III trials on prostate SBRT and the promising results of …

The march toward single-fraction stereotactic body radiotherapy for localized prostate cancer—Quo Vadimus?

WL Ong, A Loblaw - World Journal of Urology, 2023 - Springer
Purpose Stereotactic body radiotherapy (SBRT) is an emerging treatment option for
localized prostate cancer. There is increasing interest to reduce the number of fractions for …

Extreme hypofractionation with SBRT in localized prostate cancer

MA Gómez-Aparicio, J Valero, B Caballero, R García… - Current …, 2021 - mdpi.com
Prostate cancer is the most commonly diagnosed cancer among men around the world.
Radiotherapy is a standard of care treatment option for men with localized prostate cancer …

Evaluating the tolerability of a simultaneous focal boost to the gross tumor in prostate SABR: a toxicity and quality-of-life comparison of two prospective trials

Y Alayed, M Davidson, S Liu, W Chu, E Tseng… - International Journal of …, 2020 - Elsevier
Purpose Dose-escalated stereotactic ablative radiotherapy (SABR) to the whole prostate
may be associated with better outcomes but has a risk of increased toxicity. An alternative …