Abstract The [FeFe]-and [NiFe]-hydrogenases catalyze the formal interconversion between
hydrogen and protons and electrons, possess characteristic non-protein ligands at their …

Ever since the discovery of hydrogenases over 90 years ago (Stephenson and Stickland,
1931), their structure and mechanism of action have been intensively investigated. Of the …

The plant terpenoids limonene (C10H16) and α-bisabolene (C15H24) are hydrocarbon
precursors to a range of industrially relevant chemicals. High-titer microbial synthesis of …

[FeFe]-hydrogenases are complex metalloenzymes, key to microbial energy metabolism in
numerous organisms. During anaerobic metabolism, they dissipate excess reducing …

Hydrogen production is a vital metabolic process for many anaerobic organisms, and the
enzyme responsible, hydrogenase, has been studied since the 1930s. A novel subfamily …

Fermentation or anoxic metabolism allows unicellular organisms to colonize environments
that become anoxic. Free-living unicellular algae capable of a photoautotrophic lifestyle can …

The precise electrochemical features of metal cofactors that convey the functions of redox
enzymes are essentially determined by the specific interaction pattern between cofactor and …

Anaerobic metabolic pathways allow unicellular organisms to tolerate or colonize anoxic
environments. Over the past ten years, genome sequencing projects have brought a new …

The overexpression of the RuBisCO (rbc) gene has recently become an achievable strategy
for increasing cyanobacterial biomass and overcoming the biocompound production …

Chlamydomonas reinhardtii (Chlamydomonas throughout) encodes two [FeFe]-
hydrogenases, designated HYDA1 and HYDA2. While HYDA1 is considered the dominant …