Dendritic cells (DCs) bridge innate and adaptive immunity. Their main function is to present
antigens to prime T cells and initiate and shape adaptive responses. Antigen presentation …

Cancer is the leading cause of death globally and there is a worldwide cancer epidemic.
Immunotherapy has emerged as a promising anticancer therapy. In particular, oncolytic …

Introduction Over the past four years, the COVID-19 pandemic has posed serious global
health challenges. The severe form of disease and death resulted from the failure of immune …

Bronchopneumonia is a common respiratory disease in livestock. Mannheimia haemolytica
is considered the main causative pathogen leading to lung damage in sheep, with …

Introduction: Immune-checkpoint inhibitor (ICPI) drugs, which include antibodies against
CTLA-4, PD-1 and PD-L1, have been shown to induce durable complete responses in a …

Background Unexplained recurrent spontaneous pregnancy loss (URPL) lacks effective
treatment and reliable early diagnosis and prediction. Immunologic dysfunction can be an …

Background: Bursa of Fabricius is the acknowledged central humoral immune organ. The
bursal-derived peptides play the important roles on the immature B cell development and …

This report describes efforts to understand the immune mechanism of action that led to a
complete response in a patient with progressive, refractory, metastatic melanoma after …

Simple Summary The actin-bundling protein Fascin is upregulated in many types of cancers,
including adult T-cell leukemia/lymphoma, a tumor induced by the oncogenic retrovirus …

Simple Summary Expression of the actin-bundling protein Fascin-1 (Fscn1) is largely
restricted to neuronal cells and to activated dendritic cells (DCs). DCs are important inducers …