The vertebrate musculoskeletal system is known to be formed by mesenchymal stem cells
condensing into tissue elements, which then differentiate into cartilage, bone …

A process is provided of introducing an RNA into a living cell to inhibit gene expression of a
target gene in that cell. The process may be practiced ex vivo or in vivo. The RNA has a …

Apolipoprotein (apo) E3-Leiden, described in a large Dutch family, is associated with a
dominantly inherited form of familial dysbetalipoproteinemia. To study the effect of the …

Inhibitory regulators of apoptosis play a critical role in the responsiveness of tumour cells to
cytotoxic agents. The X-linked inhibitor of apoptosis protein (XIAP) is a member of a novel …

The prototype JHM strain of murine hepatitis virus (MHV) is an enveloped, RNA-containing
coronavirus that has been selected in vivo for extreme neurovirulence. This virus encodes …

Expression of the intrinsic cellular caspase inhibitor XIAP is regulated primarily at the level of
protein synthesis. The 5′ untranslated region harbours an Internal Ribosome Entry Site …

1992.* particular discloses the use of Site-specific recombinases Such as Flp recombinase
to accomplish in Vivo recombina tion at engineered chromosomal FRTSites, thereby forming …

Human and mouse embryonic stem (ES) cells have the capacity to differentiate into
derivatives of all three germ layers, suggesting novel therapies for degenerative, metabolic …

(57) ABSTRACT A transcutaneous immunization System where the topical application of an
adjuvant and an antigen or nucleic acid encoding for an antigen, to intact skin induces a …

The vaccinia virus (VV) B8R gene encodes a secreted protein with homology to the gamma
interferon (IFN-γ) receptor. In vitro, the B8R protein binds to and neutralizes the antiviral …