The hippo pathway in prostate cancer

O Salem, CG Hansen - Cells, 2019 - mdpi.com
Despite recent efforts, prostate cancer (PCa) remains one of the most common cancers in
men. Currently, there is no effective treatment for castration-resistant prostate cancer …

Healthcare professional perceived barriers and facilitators to discussing sexual wellbeing with patients after diagnosis of chronic illness: A mixed-methods evidence …

SR O'Connor, J Connaghan, R Maguire… - Patient Education and …, 2019 - Elsevier
Objectives To explore healthcare professional perceived barriers and facilitators to
discussing sexual health and wellbeing with patients after diagnosis of chronic illness …

[HTML][HTML] Quality of life after bladder cancer: a cross-sectional survey of patient-reported outcomes

JWF Catto, A Downing, S Mason, P Wright, K Absolom… - European urology, 2021 - Elsevier
Background Little is known about health-related quality of life (HRQOL) following treatment
for bladder cancer (BC). Objective To determine this, we undertook a cross-sectional survey …

[HTML][HTML] Reconsidering the trade-offs of prostate cancer screening

JE Shoag, YA Nyame, R Gulati, R Etzioni… - The New England …, 2020 - ncbi.nlm.nih.gov
After the widespread adoption of prostate-specific antigen (PSA) screening in the early
1990s, prostate cancer diagnoses increased rapidly while death rates halved over the …

Polygenic risk-tailored screening for prostate cancer: A benefit–harm and cost-effectiveness modelling study

T Callender, M Emberton, S Morris… - Advances in …, 2021 - api.taylorfrancis.com
Screening with a prostate-specific antigen (PSA) test could reduce death from prostate
cancer in some men but at the cost of substantial numbers overdiagnosed, as well as false …

[HTML][HTML] Darolutamide and health-related quality of life in patients with non-metastatic castration-resistant prostate cancer: an analysis of the phase III ARAMIS trial

MR Smith, N Shore, TL Tammela, A Ulys… - European Journal of …, 2021 - Elsevier
Background In the ARAMIS trial, darolutamide plus androgen deprivation therapy (ADT)
versus placebo plus ADT significantly improved metastasis-free survival (MFS), overall …

Mental health outcomes in a population-based cohort of patients with prostate cancer

S Hu, CP Chang, J Snyder, V Deshmukh… - JNCI: Journal of the …, 2024 - academic.oup.com
Background Few studies have evaluated mental health disorders comprehensively among
patients with prostate cancer on long-term follow-up. The primary aim of our study was to …

Value-based healthcare in urology: a collaborative review

C Reitblat, PA Bain, ME Porter, DN Bernstein… - European Urology, 2021 - Elsevier
Context In response to growing concerns over rising costs and major variation in quality,
improving value for patients has been proposed as a fundamentally new strategy for how …

[HTML][HTML] Analysis of patient-reported outcomes in the approval of novel oncology drugs in the United States, 2017–2022

C Ge, K Guo, Y Li, G Li, H Zhang, J Yang, Y Liu… - …, 2023 - thelancet.com
Background With the growing notion of patient-focused drug development, the quality of life
and other patient-reported outcomes (PROs) of cancer patients are gaining considerable …

Decision regret in men living with and beyond nonmetastatic prostate cancer in the United Kingdom: A population‐based patient‐reported outcome study

S Wilding, A Downing, P Selby, W Cross… - Psycho …, 2020 - Wiley Online Library
Objective Clinical options for managing nonmetastatic prostate cancer (PCa) vary. Each
option has side effects associated with it, leading to difficulty in decision‐making. This study …