Manufactured extracellular vesicles as human therapeutics: challenges, advances, and opportunities

S Estes, K Konstantinov, JD Young - Current Opinion in Biotechnology, 2022 - Elsevier
Highlights•EVs come in two classes: native or engineered with defined therapeutic
entity.•Advances in engineering EVs to load cargo have enhanced potency.•High-density …

Alternative biological sources for extracellular vesicles production and purification strategies for process scale-up

S Giancaterino, C Boi - Biotechnology Advances, 2023 - Elsevier
Extracellular vesicles (EVs) are phospholipidic bi-layer enclosed nanoparticles secreted
naturally by all cell types. They are attracting increasing attention in the fields of …

Large‐scale production of extracellular vesicles: Report on the “massivEVs” ISEV workshop

L Paolini, M Monguió‐Tortajada, M Costa, F Antenucci… - 2022 - Wiley Online Library
Extracellular vesicles (EVs) large‐scale production is a crucial point for the translation of
EVs from discovery to application of EV‐based products. In October 2021, the International …

Production of recombinant and therapeutic proteins in microalgae

A Banerjee, V Ward - Current Opinion in Biotechnology, 2022 - Elsevier
Highlights•Microalgae based protein expression systems are highly promising.•
Chlamydomonas reinhardtii and Phaetodactylum tricornutum are the most prevalent species …

Biosynthesis and Antimicrobial Evaluation of Zinc Oxide Nanoparticles Using Chlorella vulgaris Biomass against Multidrug-Resistant Pathogens

MH Morowvat, K Kazemi, MA Jaberi, A Amini… - Materials, 2023 - mdpi.com
The rampant increase in antibiotic resistance has created a global barrier to the treatment of
multidrug-resistant infections. Biogenic synthesis of nanomaterials is a novel approach to …

Natural compounds-based nanomedicines for cancer treatment: Future directions and challenges

T Andreani, R Cheng, K Elbadri, C Ferro… - Drug Delivery and …, 2024 - Springer
Several efforts have been extensively accomplished for the amelioration of the cancer
treatments using different types of new drugs and less invasives therapies in comparison …

Isolation of extracellular vesicles from microalgae: a renewable and scalable bioprocess

A Paterna, E Rao, G Adamo, S Raccosta… - … in Bioengineering and …, 2022 - frontiersin.org
Extracellular vesicles (EVs) play a crucial role as potent signal transducers among cells, with
the potential to operate cross-species and cross-kingdom communication. Nanoalgosomes …

DNA nanomaterial‐empowered surface engineering of extracellular vesicles

X Yao, D He, P Wei, Z Niu, H Chen, L Li… - Advanced …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are cell‐secreted biological nanoparticles that are critical
mediators of intercellular communication. They contain diverse bioactive components, which …

Extracellular vesicles from the microalga Tetraselmis chuii are biocompatible and exhibit unique bone tropism along with antioxidant and anti-inflammatory properties

G Adamo, P Santonicola, S Picciotto… - Communications …, 2024 - nature.com
Extracellular vesicles (EVs) are membrane-enclosed bio-nanoparticles secreted by cells
and naturally evolved to transport various bioactive molecules between cells and even …

[HTML][HTML] Functional foods to counterbalance low-grade inflammation and oxidative stress in cardiovascular diseases: a multilayered strategy combining food and …

D Granato - Current Opinion in Food Science, 2022 - Elsevier
Highlights•Cardiovascular diseases (CVDs) are the main leading cause of mortality
worldwide, but can be prevented.•Functional foods (FF) should be produced to mitigate …