Background The overall clinical benefit of thiazolidinediones (TZDs) as a treatment for
hyperglycaemia can be difficult to assess because of the risk of congestive heart failure due …

Type 2 diabetes mellitus, a global epidemic, is largely attributed to metabolic syndrome and
its clustering of cardiovascular risk factors including abdominal obesity, dyslipidemia …

ContextCarotid artery intima-media thickness (CIMT) is a marker of coronary atherosclerosis
and independently predicts cardiovascular events, which are increased in type 2 diabetes …

The cerebral neuropathology of Type 2 diabetes (CNDM2) has not been positively defined.
This review includes a description of CNDM2 research from before the 'Pubmed Era'. Recent …

Thiazolidinediones (TZDs) have been used for the treatment of hyperglycaemia in type 2
diabetes for the past 10 years. They may delay the development of type 2 diabetes in …

Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription
factor that plays a critical role in metabolism. Thiazolidinediones, high-affinity PPARγ ligands …

Cholesterol efflux is the initial step in the reverse cholesterol transport pathway by which
excess cholesterol in peripheral cells is exported and subsequently packaged into high …

Background—Fat inflammation may play an important role in comorbidities associated with
obesity such as atherosclerosis. Methods and Results—To first establish feasibility of fat …

The metabolic syndrome (MetS) is defined by a set of metabolic risk factors, including insulin
resistance, central obesity, dyslipidemia, hyperglycemia, and hypertension for type 2 …

OBJECTIVE This study aimed to verify whether the decreased vascular endothelial growth
factor (VEGF)–to–pigment epithelium–derived factor (PEDF) ratio can serve as an indicator …