Neonatal infectious diseases: evaluation of neonatal sepsis

A Camacho-Gonzalez, PW Spearman… - Pediatric …, 2013 - pediatric.theclinics.com
Neonatal sepsis remains a feared and serious complication, especially among very low birth
weight (VLBW) preterm infants. Neonatal sepsis is divided into early-onset and late-onset …

Neonatal sepsis: an old problem with new insights

BA Shah, JF Padbury - Virulence, 2014 - Taylor & Francis
Neonatal sepsis continues to be a common and significant health care burden, especially in
very-low-birth-weight infants (VLBW< 1500 g). Though intrapartum antibiotic prophylaxis has …

Low HDL and high triglycerides predict COVID-19 severity

L Masana, E Correig, D Ibarretxe, E Anoro, JA Arroyo… - Scientific reports, 2021 - nature.com
Lipids are indispensable in the SARS-CoV-2 infection process. The clinical significance of
plasma lipid profile during COVID-19 has not been rigorously evaluated. We aim to …

New approaches to sepsis: molecular diagnostics and biomarkers

K Reinhart, M Bauer, NC Riedemann… - Clinical microbiology …, 2012 - Am Soc Microbiol
Sepsis is among the most common causes of death in hospitals. It arises from the host
response to infection. Currently, diagnosis relies on nonspecific physiological criteria and …

Longitudinal development of the gut microbiome and metabolome in preterm neonates with late onset sepsis and healthy controls

CJ Stewart, ND Embleton, ECL Marrs, DP Smith… - Microbiome, 2017 - Springer
Background Late onset sepsis (LOS) in preterm infants is associated with considerable
morbidity and mortality. While studies have implicated gut bacteria in the aetiology of the …

Necrotizing enterocolitis: It's not all in the gut

AL Meister, KK Doheny… - Experimental biology and …, 2020 - journals.sagepub.com
Necrotizing enterocolitis is the leading cause of death due to gastrointestinal disease in
preterm neonates, affecting 5–12% of neonates born at a very-low birth weight. Necrotizing …

Time for a neonatal-specific consensus definition for sepsis

JL Wynn, HR Wong, TP Shanley… - Pediatric Critical Care …, 2014 - journals.lww.com
Objective: To review the accuracy of the pediatric consensus definition of sepsis in term
neonates and to determine the definition of neonatal sepsis used. Study Selection: The …

An integrated clinico-metabolomic model improves prediction of death in sepsis

RJ Langley, EL Tsalik, JC Velkinburgh… - Science translational …, 2013 - science.org
Sepsis is a common cause of death, but outcomes in individual patients are difficult to
predict. Elucidating the molecular processes that differ between sepsis patients who survive …

Diagnostics for neonatal sepsis: current approaches and future directions

PY Iroh Tam, CM Bendel - Pediatric research, 2017 - nature.com
Progress has been made in the reduction of morbidity and mortality from neonatal sepsis.
However, diagnosis continues to rely primarily on conventional microbiologic techniques …

Surgical necrotizing enterocolitis

JR Robinson, EJ Rellinger, LD Hatch… - Seminars in …, 2017 - Elsevier
Although currently available data are variable, it appears that the incidence of surgical
necrotizing enterocolitis (NEC) has not decreased significantly over the past decade …