Opioid use in chronic pain treatment is complex, as patients may derive both benefit and
harm. Identification of individuals currently using opioids in a problematic way is important …

Background Gabapentinoid (pregabalin and gabapentin) abuse is increasingly being
reported. Objective To assess the extent of gabapentinoid abuse, characteristics of typical …

Chronic pain and prescription opioid abuse are extremely prevalent both in this country and
worldwide. Consequences of opioid misuse can be life-threatening with significant morbidity …

Introduction: Opioids are the oldest and most potent drugs for the treatment of severe pain,
but they are burdened by detrimental side effects such as respiratory depression, addiction …

Opioid use disorder (OUD) and its consequences are a major public health concern. The
partial agonist buprenorphine is a safe and effective treatment for OUD, but concerns about …

Background Several case reports and epidemiological studies have raised concern about
the abuse potential of pregabalin, the use of which has increased substantially over the last …

The opioid epidemic is a public health problem associated with a host of negative outcomes.
Although clinicians recognize covariation between opioid misuse with anxiety and …

Background Opioids are frequently prescribed for chronic low back pain (CLBP), but there is
little prospective data on which patient subgroups may benefit. Psychiatric comorbidity, such …

Aims The aim of this study was to assess the use and factors associated with the misuse of
gabapentin and pregabalin in the general French population, through a cohort study in the …

Increasing mortality and morbidity associated with opioid analgesics has led to concerns
about their misuse and abuse, even when obtained through a prescription. These concerns …