Bone marrow aspirate concentrate (BMAC) and adipose-derived stromal vascular fraction
(ADSVF) are the most marketed stem cell therapies to treat a variety of conditions in the …

The use of bone marrow stromal cells (BMSCs) for bone defect repair has shown great
promise due to their differentiation potential. However, isolating the BMSCs from various cell …

Background: Mesenchymal stromal cells (MSCs) and fibroblasts show similar morphology,
surface marker expression, and proliferation, differentiation, and immunomodulatory …

Uncultured, unmodified, autologous, adipose-derived regenerative cells (UA-ADRCs) are a
safe and effective treatment option for various musculoskeletal pathologies. However, it is …

The use of concentrated bone marrow aspirate (cBMA) for the treatment of common
musculoskeletal conditions continues to increase and remains one of the most frequently …

The heterogeneity of stem cells is a significant factor inhibiting their clinical application, as
different cell subpopulations may exhibit substantial differences in biological functions. We …

Stem cells are investigated for several reasons. In this article, the basic concepts and
principles of stem cell biology as well as some key considerations for moving from bench to …

Human periosteal skeletal stem cells (P-SSCs) are critical for cortical bone maintenance and
repair. However, their in vivo identity, molecular characteristics, and specific markers remain …

Osteonecrosis of the femoral head (ONFH) is a progressive degenerative disease that
ultimately requires a total hip replacement. Mesenchymal stromal/stem cells (MSCs) …

The inheritance of recurrent patellar dislocation (RPD) is known, but the susceptible gene
remains unidentified. Here, we performed the first whole exome sequencing (WES) cohort …