The past decade has witnessed exponentially growing interest in the lateral habenula (LHb)
owing to new discoveries relating to its critical role in regulating negatively motivated …

Neuronal nicotinic acetylcholine receptors (nAChRs) regulate the rewarding actions of
nicotine contained in tobacco that establish and maintain the smoking habit. nAChRs also …

The habenula complex is appreciated as a critical regulator of motivated and pathological
behavioral states via its output to midbrain nuclei. Despite this, transcriptional definition of …

The habenula (Hb) is a phylogenetically old epithalamic structure differentiated into two
nuclear complexes, the medial (MHb) and lateral habenula (LHb). After decades of search …

Independent from homeostatic needs, the consumption of foods originating from
hyperpalatable diets is defined as hedonic eating. Hedonic eating can be observed in many …

The habenula (Hb) is an epithalamic structure differentiated into two nuclear complexes,
medial (MHb) and lateral habenula (LHb). After decades of relative neglect, interest in the …

The orphan G-protein-coupled receptor GPR139 is highly expressed in the habenula, a
small brain nucleus that has been linked to depression, schizophrenia (SCZ), and substance …

G protein-coupled receptors (GPCRs) are a large family of cell surface receptors that are the
targets for many different classes of pharmacotherapy. The islets of Langerhans are central …

The GPR139 receptor is an orphan G-protein-coupled receptor (GPCR) mainly found in the
central nervous system and is a potential therapeutic target for the treatment of …

Over the past 20 years, substantive research has firmly implicated the lateral habenula in
myriad neural processes including addiction, depression, and sleep. More recently …