The inner ear is one of the most morphologically elaborate tissues in vertebrates, containing
a group of mechanosensitive sensory organs that mediate hearing and balance. These …

Cranial placodes (which include the adenohypophyseal, olfactory, lens, otic, lateral line,
profundal/trigeminal, and epibranchial placodes) give rise to many sense organs and …

Rare genetic diseases are a group of pathologies with often unmet clinical needs. Even if
rare by a single genetic disease (from 1/2000 to 1/more than 1,000,000), the total number of …

Vertebrate hearing and balance are based in complex asymmetries of inner ear structure.
Here, we identify retinoic acid (RA) as an extrinsic signal that acts directly on the ear …

Our ears are remarkable sensory organs, providing the important senses of balance and
hearing. The complex structure of the inner ear, or 'labyrinth', along with the assorted …

The third edition of Human Malformations and Related Anomalies is a comprehensive
reference and clinical guide to significant human malformations. Authored by 40 authorities …

The inner ear epithelium, with its complex array of sensory, non-sensory, and neuronal cell
types necessary for hearing and balance, is derived from a thickened patch of head …

What information-processing strategies and general principles are sufficient to enable self-
organized morphogenesis in embryogenesis and regeneration? We designed and analyzed …

Eye and inner ear diseases are the most common sensory impairments that greatly impact
quality of life. Zebrafish have been intensively employed to understand the fundamental …

Proper spatial control of neurogenesis in the inner ear ensures the precise innervation of
mechanotransducing cells and the propagation of auditory and equilibrium stimuli to the …