Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a rare
monogenic autoimmune disease with variable clinical manifestations, ranging from early …

Immune dysregulation, polyendocrinopathy, and enteropathy, X-linked (IPEX) syndrome is a
rare disorder that has become a model of monogenic autoimmunity. IPEX is caused by …

Inflammatory bowel disease (IBD) is a chronic relapsing disorder of the gastrointestinal tract,
while the present therapeutic efficacy is insufficient. In recent years, numerous studies have …

Very early onset inflammatory bowel disease (VEO-IBD) represents approximately 25% of
cases of IBD-like colitis occurring during childhood and, by definition, it is characterized by …

Immune‐mediated inflammatory diseases (IMIDs) are a diverse group of complex
inflammatory diseases that result from dysregulated immune pathways and can involve any …

Inflammatory bowel disease (IBD) is a group of complex, multifactorial disorders
characterized by chronic inflammation of the gastrointestinal tract. The three subtypes of IBD …

Pediatric intestinal development is immature, vulnerable to external influences and produce
a variety of intestinal diseases. At present, breakthroughs have been made in the treatment …

The human gut microbiota comprises wide diversity of microorganisms consisting of
bacteria, viruses and eukaryotes. This normal flora plays a critical role in maintaining the …

Background Molecular diagnosis of early onset inflammatory bowel disease (IBD) is very
important for adopting suitable treatment strategies. Owing to the sparse data available, this …

This was a retrospective cohort study aimed at identifying parameters measured at
diagnosis of pediatric IBD to predict subsequent biologic therapy, as an equivalent to an …