Undesignable RNA Structure Identification via Rival Structure Generation and Structure Decomposition
RNA design is the search for a sequence or set of sequences that will fold into predefined
structures, also known as the inverse problem of RNA folding. While numerous RNA design …
structures, also known as the inverse problem of RNA folding. While numerous RNA design …
Messenger and non-coding rna design via expected partition function and continuous optimization
The tasks of designing messenger RNAs and non-coding RNAs are discrete optimization
problems, and several versions of these problems are NP-hard. As an alternative to …
problems, and several versions of these problems are NP-hard. As an alternative to …
Partial RNA design
Motivation RNA design is a key technique to achieve new functionality in fields like synthetic
biology or biotechnology. Computational tools could help to find such RNA sequences but …
biology or biotechnology. Computational tools could help to find such RNA sequences but …
Scalable Identification of Minimum Undesignable RNA Motifs on Loop-Pair Graphs
T Zhou, WY Tang, DH Mathews, L Huang - arXiv preprint arXiv …, 2024 - arxiv.org
Motivation: RNA design aims to find at least one sequence that folds with the highest
probability into a designated target structure, but some structures are undesignable in the …
probability into a designated target structure, but some structures are undesignable in the …