A major consequence of traumatic brain and spinal cord injury is the loss of the myelin
sheath, a cholesterol-rich layer of insulation that wraps around axons of the nervous system …

Breast cancer is the most frequently diagnosed malignancy in American women. While
significant progress has been made in the development of modern diagnostic tools and …

Small interfering RNA (siRNA)–based therapeutics can mitigate the long-term sequelae of
traumatic brain injury (TBI) but suffer from poor permeability across the blood-brain barrier …

Traumatic brain injury (TBI) is a major health and socio-economic problem, but no
pharmacological agent is currently approved for the treatment of acute TBI. Thus, there is a …

Microglia polarization plays an important role in poststroke recovery. Inhibition of
proinflammatory (M1) polarization and promotion of anti-inflammatory (M2) polarization of …

Although many patients do not receive reperfusion therapy because of delayed presentation
and/or severity and location of infarct, new reperfusion approaches are expanding the …

Patients enrolled in clinical trials for traumatic brain injury (TBI) may present with
heterogeneous features over a range of injury severity, such as diffuse axonal injury …

Background Maclpil is a proinflammatory long non-coding RNA highly expressed on
monocyte-derived macrophages in the ischemic brain. This study investigated the impact …

2022-01-07 First worldwide family litigation filed litigation Critical https://patents. darts-ip.
com/? family= 53189202&utm_source= google_patent&utm_medium …

Background and Purpose—Intracerebral hemorrhage (ICH) is a subtype of stroke with
highest mortality and morbidity. Pronounced inflammation plays a significant role in the …