Autophagy is an evolutionarily conserved, lysosome-dependent catabolic process whereby
cytoplasmic components, including damaged organelles, protein aggregates and lipid …

Ferroptosis is a recently discovered essential type of cell death that is mainly characterized
by iron overload and lipid peroxidation. Emerging evidence suggests that ferroptosis is a …

The increasing emergence and dissemination of multidrug resistant (MDR) bacterial
pathogens accelerate the desires for new antibiotics. Natural products dominate the …

Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

Caloric restriction and intermittent fasting prolong the lifespan and healthspan of model
organisms and improve human health. The natural polyamine spermidine has been similarly …

The increase in life expectancy has boosted the incidence of age-related pathologies
beyond social and economic sustainability. Consequently, there is an urgent need for …

Mitochondrial dysfunction constitutes one of the hallmarks of aging and is characterized by
irregular mitochondrial morphology, insufficient ATP production, accumulation of …

Flavonoids, commonly found in various plants, are a class of polyphenolic compounds
having a basic structural unit of 2-phenylchromone. Flavonoid compounds have attracted …

Cardiovascular disease is the leading cause of death in western countries. Among
cardiovascular diseases, myocardial infarction represents a life-threatening condition …

In the face of the alarming rise in global antimicrobial resistance, only a handful of novel
antibiotics have been developed in recent decades, necessitating innovations in therapeutic …