Molecular views of plasma membrane organization and dynamics are gradually changing
over the past fifty years. Dynamics of plasma membrane instigate several signaling nexuses …

Recent advances in human blastoids have opened new avenues for modeling early human
development and implantation. One limitation of our first protocol for human blastoid …

Embryonic losses constitute a major burden for reproductive efficiency of farm animals.
Pregnancy losses in ungulate species, which include cattle, pigs, sheep and goats, majorly …

Preimplantation embryos undergo zygotic genome activation and lineage specification
resulting in three distinct cell types in the late blastocyst. The molecular mechanisms …

Simple Summary The fusion between sperm and oocyte results in a zygote, which is a single
totipotent cell with the ability to develop into a functional organism. Totipotent cells can give …

microRNAs (miRNAs) are susceptible to environmental factors that might affect cellular
function and impose negative effects on female reproduction. miR-21 is the most abundant …

Vitrification and slow freezing are the two commonly used embryo cryopreservation
methods. In most studies, vitrification of intact embryos has proven superior in several …

Research question What is the gene expression pattern of prolactin receptor (PRLR) in
human pre-implantation embryos and what are its functions during the embryonic …

The self-organisation of a fertilised egg to form a blastocyst structure, which consists of three
distinct cell lineages (trophoblast, epiblast and hypoblast) arranged around an off-centre …

Early embryo development, implantation and pregnancy involve a complex dialogue
between the embryo and mother. In cattle this dialogue starts as early as days 3–4 when the …