The last three decades have brought a revolution in fluorescence microscopy. The
development of new microscopes, fluorescent labels and analysis techniques has pushed …

Hybrid small-molecule/protein fluorescent probes are powerful tools for visualizing protein
localization and function in living cells. These hybrid probes are constructed by diverse site …

Genetically encoded fluorescent biosensors have revolutionized the study of cell signaling
and metabolism, as they allow for live-cell measurements with high spatiotemporal …

Conspectus Fluorescent labels and biosensors play central roles in biological and medical
research. Targeted to specific biomolecules or cells, they allow noninvasive imaging of the …

Background The interest in using methanol as a substrate to cultivate acetogens increased
in recent years since it can be sustainably produced from syngas and has the additional …

Molecular tools enabling the control and observation of the proximity of proteins are
essential for studying the functional role of physical distance between two proteins. Here we …

Near-infrared-I/II fluorescent proteins (NIR-I/II FPs) are crucial for in vivo imaging, yet the
current NIR-I/II FPs face challenges including scarcity, the requirement for chromophore …

Biocompatible fluorescent reporters with spectral properties spanning the entire visible
spectrum are indispensable tools for imaging the biochemistry of living cells and organisms …

Fluorescent protein (FP)-based biosensors are genetically encoded tools that enable the
imaging of biological processes in the context of cells, tissues, or live animals. Though …

Synthetic near-infrared-II (NIR-II) dyes are promising for deep tissue imaging, yet they are
generally difficult to target a given biomolecule with high specificity. Furthermore, the …