Folate (vitamin B9) is found in some water-soluble foods or as a synthetic form of folic acid
and is involved in many essential biochemical processes. Dietary folate is converted into …

There are several evidences supporting the role of 5–10 methylenetetrahydrofolate
reductase (MTHFR) gene polymorphisms in breast cancer (BC). Case control association …

Objective Previous studies have found that many gene variations can be detected in both
breast cancer and ovarian cancer, which is beneficial for the elaboration of the molecular …

Background Despite conflicting results, considerable evidence suggests the association
between single nucleotide polymorphisms in MTHFR, XRCC1 and OGG1 genes and, risk of …

Background Breast cancer is one of the most common malignancies in women and is
associated with a variety of risk factors. The functional single-nucleotide polymorphism …

Background The methylenetetrahydrofolate reductase gene (MTHFR) is one of the most
investigated genes associated with breast cancer for its role in epigenetic pathways …

Aberrations in one-carbon metabolism were reported to increase breast cancer risk by
influencing the DNA synthesis and methylation of DNA and catecholamines. However, the …

Background: Cancer is a global medical challenge, and research is at its peak to understand
the unique mechanisms of cancer cells. The expanding field of epidemiology, including …

Methylenetetrahydrofolate reductase (MTHFR) plays a major role in the metabolism of
folates and homocysteine, which in turn can affect gene expression and ultimately promote …

Materials and Methods: A total of 247 breast cancer patients and 247 controls were selected
from Punjabi population for analysis using PCR-RFLP method. For meta-analysis, 67 …