Hyaluronic acid, as a natural linear polysaccharide, has attracted researchers' attention from
its initial detection and isolation from tissues in 1934 until the present day. Due to …

Hydrogels have been widely investigated in biomedical fields due to their similar physical
and biochemical properties to the extracellular matrix (ECM). Collagen and hyaluronic acid …

Bioprinting is an emerging technology with various applications in making functional tissue
constructs to replace injured or diseased tissues. It is a relatively new approach that …

As a major polysaccharide component of the extracellular matrix, hyaluronan plays essential
roles in the organization of tissue architecture and the regulation of cellular functions, such …

Hyaluronic acid (HA) is a large non-sulphated glycosaminoglycan that is an important
component of extracellular matrix (ECM) and a biodegradable polymer. Due to a variation in …

Cartilage homeostasis is governed by articular chondrocytes via their ability to modulate
extracellular matrix production and degradation. In turn, chondrocyte activity is regulated by …

Hyaluronan (HA) is a critical element of the extracellular matrix (ECM). The regulated
synthesis and degradation of HA modulates the ECM chemical and physical properties that …

All cells sense and integrate mechanical and biochemical cues from their environment to
orchestrate organismal development and maintain tissue homeostasis …

Hyaluronic acid (HA) is a glycosaminoglycan widely distributed in the human body,
especially in body fluids and the extracellular matrix of tissues. It plays a crucial role not only …

In this editorial to MDPI Pharmaceuticals special issue “Glycosaminoglycans and
Proteoglycans” we describe in outline the common structural features of …