Glycogen synthase kinase-3β (GSK-3β), a serine/threonine protein kinase, is a complex
regulator of numerous cellular functions. GSK-3β is a unique kinase which is constitutively …

The serine/threonine kinase glycogen synthase kinase-3 (GSK-3) was initially identified
because of its key role in the regulation of glycogen synthesis. However, it is now well …

As a kinase at the crossroads of numerous metabolic and cell growth signaling pathways,
glycogen synthase kinase-3 beta (GSK-3β) is a highly desirable therapeutic target in cancer …

Background Glycogen synthase kinase-3 (GSK-3) is a serine/threonine kinase with multiple
roles in tumour growth, cell invasion and metastasis. We have previously established GSK-3 …

Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a predominantly fatal common
malignancy with inadequate treatment options. Glycogen synthase kinase 3β (GSK-3β) is an …

Glycogen synthase kinase-3β (GSK-3β) is a conserved serine/threonine kinase that
participates in the transmission of multiple signaling pathways and plays an important role in …

Glycogen synthase kinase 3β (GSK 3β), a multifunctional serine and threonine kinase, plays
a critical role in a variety of cellular activities, including signaling transduction, protein and …

Background: Cholangiocarcinoma (CCA) is a type of hepatobiliary cancer characterized by
uncontrolled cell proliferation, with a poor prognosis and high mortality. Nobiletin (NBT) is a …

Glycogen synthase kinase 3β (GSK-3β) is a widely investigated molecular target for
numerous diseases including Alzheimer's disease, cancer, and diabetes mellitus. Inhibition …

Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with a median
survival of 3 years after diagnosis. Although the etiology of IPF is unknown, it is …