Osteomyelitis remains one of the greatest risks in orthopaedic surgery. Although many
organisms are linked to skeletal infections, Staphylococcus aureus remains the most …

Musculoskeletal trauma leading to broken and damaged bones and soft tissues can be a life-
threating event. Modern orthopaedic trauma surgery, combined with innovation in medical …

Osteomyelitis is a devastating disease caused by microbial infection of bone. While the
frequency of infection following elective orthopedic surgery is low, rates of reinfection are …

Biomedical implants have been widely used in various orthopedic treatments, including total
hip arthroplasty, joint arthrodesis, fracture fixation, non-union, dental repair, etc. The modern …

Musculoskeletal infections (MSKI) remain the bane of orthopedic surgery, and result in
grievous illness and inordinate costs that threaten healthcare systems. As prevention …

Osteomyelitis, or inflammation of bone, is most commonly caused by invasion of bacterial
pathogens into the skeleton. Bacterial osteomyelitis is notoriously difficult to treat, in part …

Approximately 40% of treatments of chronic and recurrent osteomyelitis fail in part due to
bacterial persistence. Staphylococcus aureus, the predominant pathogen in human …

Bone is a hard yet dynamic tissue with remarkable healing capacities. Research to date has
greatly advanced the understanding of how bone heals and has led to marked success in …

Staphylococcus aureus is a highly successful Gram-positive pathogen capable of causing
both superficial and invasive, life-threatening diseases. Of the invasive disease …

Bacteria have developed a wealth of strategies to avoid and resist the action of antibiotics,
one of which involves pathogens invading and forming reservoirs within host cells. Due to …