Inhaled corticosteroids have revolutionized the treatment of asthma and have now become
the mainstay of therapy for patients with chronic disease (1). In a supplement to this journal …

The delivery of drugs by inhalation is an integral component of asthma and chronic
obstructive pulmonary disease (COPD) management. However, even with effective inhaled …

Background Patients with mild asthma often rely on inhaled short-acting β2-agonists for
symptom relief and have poor adherence to maintenance therapy. Another approach might …

Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A
Task Force, supported by the European Respiratory Society and American Thoracic Society …

Background The issue of whether regular use of an inhaled β 2-adrenergic agonist worsens
airflow and clinical outcomes in asthma is controversial. Retrospective studies have …

Background In a previous study, we found that two years of treatment with an inhaled
corticosteroid, budesonide, was more effective than treatment with an inhaled β2-agonist …

Objectives: To provide physicians with current guidelines for the diagnosis and optimal
management of asthma in children and adults, including pregnant women and the elderly, in …

Mast cells (MC s) play a central role in tissue homoeostasis, sensing the local environment
through numerous innate cell surface receptors. This enables them to respond rapidly to …

Objective: To assess the effect of cardioselective β-blockers on respiratory function of
patients with reactive airway disease. Data Sources: Comprehensive searches of the …

Background Inhaled β-agonists are the most commonly used treatment for asthma, but data
suggest that regularly scheduled use of these agents may have a deleterious effect on the …