Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) is the most common and best known monogenic small …

Anderson–Fabry disease (AFD) is a genetic sphingolipidosis involving virtually the entire
body. Among its manifestation, the involvement of the central and peripheral nervous system …

Objective: To characterize earlier damage pattern of white matter (WM) microstructure in
cerebral small vessel disease (CSVD) and its relationship with cognitive domain …

Enzyme replacement therapy has drastically changed prospects of patients with Pompe
disease, a progressive metabolic myopathy. As classic infantile patients survive due to …

Recurrent stroke and cognitive impairment are the primary features of patients with cerebral
autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy …

In addition to the development of beta amyloid plaques and neurofibrillary tangles,
Alzheimer's disease (AD) involves the loss of connecting structures including degeneration …

Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) mainly manifests with cognitive impairment. Cognitive …

Background Peak width of skeletonized mean diffusivity (PSMD) is a novel and fully
automated, MRI biomarker, which has shown clinical relevance in cerebral small vessel …

Objective Several evidences demonstrated the role of white matter (WM) lesions in the
pathogenesis of Vascular Parkinsonism (VP), a clinical entity characterized by parkinsonism …

Background Patients with cerebral small vessel disease may suffer from varying levels of
cognitive deficit and may progress on to vascular dementia. The extent of involvement, as …