Systemic lupus erythematosus (SLE) is associated with a broad spectrum of clinical and
immunologic manifestations, of which lupus nephritis is the most common cause of morbidity …

Unconventional T cells are a diverse and underappreciated group of relatively rare
lymphocytes that are distinct from conventional CD4+ and CD8+ T cells, and that mainly …

Glomerular diseases are common and important. They can arise from systemic inflammatory
or metabolic diseases that affect the kidney. Alternately, they are caused primarily by local …

It has become evident that nonlymphoid tissues are populated by distinct subsets of innate
and adaptive lymphocytes that are characterized by minimal exchange with recirculating …

Chronic kidney disease, secondary to renal fibrogenesis, is a burden on public health. There
is a need to explore new therapeutic pathways to reduce renal fibrogenesis. To study this …

Objectives Anti-glomerular basement membrane (GBM) disease is a rare autoantibody-
mediated disorder presenting as rapidly progressive glomerulonephritis, and often with …

Transcriptome analysis by RNA-seq technology allows novel insights into gene expression
and regulatory networks in health and disease. To better understand the molecular basis of …

The pathophysiology of anti-glomerular basement membrane (anti-GBM) disease before
clinical presentation is unknown. The presence of anti-GBM, anti-proteinase 3 (PR3), and …

Antiglomerular basement membrane (anti-GBM) disease is an autoimmune disorder that
mostly presents as raised titers of antibodies against the GBM, rapidly progressive …

This review is based on our experience with ten patients diagnosed with Goodpasture's
disease (GD). Six of the patients presented with combined renal and pulmonary …